Description
interleukin 6 signal transducer (gp130, oncostatin M receptor) [Source:HGNC Symbol;Acc:6021]
Gene Synonyms
CD130, CDW130, GP130, IL-6RB
Location
Chromosome 5: 55,230,923-55,290,821 reverse strand.
GRCh37:CM000667.1
About this gene
This gene has 16 transcripts (splice variants), 5 paralogues and is associated with 50 phenotypes.
Transcripts
| Transcript ID | Name | bp | Protein | Translation ID | Biotype | CCDS | UniProt Match | RefSeq | Flags |
|---|---|---|---|---|---|---|---|---|---|
| ENST00000381298.2 | IL6ST-001 | 9057 | 918aa | ENSP00000370698.2 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS3971 | P40189 | NM_175767.2 | A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000336909.5 | IL6ST-201 | 8750 | 918aa | ENSP00000338799.5 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS3971 | P40189 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000381287.4 | IL6ST-202 | 8667 | 329aa | ENSP00000370687.4 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS47209 | P40189 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000502326.3 | IL6ST-011 | 3007 | 918aa | ENSP00000462158.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS3971 | P40189 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000381294.3 | IL6ST-012 | 2574 | 857aa | ENSP00000370694.3 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS54856 | P40189 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000536319.1 | IL6ST-204 | 2491 | 329aa | ENSP00000444456.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS47209 | P40189 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000522633.2 | IL6ST-007 | 1878 | 329aa | ENSP00000435399.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS47209 | P40189 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000381293.2 | IL6ST-003 | 612 | 203aa | ENSP00000370693.2 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | Q5FC05 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, | |
| ENST00000381286.3 | IL6ST-005 | 201 | 66aa | ENSP00000370686.3 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | Q5FC02 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, | |
| ENST00000396816.1 | IL6ST-203 | 168 | 55aa | ENSP00000463896.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | Q5FC07 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, | |
| ENST00000503773.2 | IL6ST-006 | 3031 | 333aa | ENSP00000426224.2 | Nonsense mediated decay | D6RH03 | - | - | |
| ENST00000577363.1 | IL6ST-004 | 282 | No protein | - | Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript | - | - | - | |
| ENST00000423954.3 | IL6ST-008 | 153 | No protein | - | Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript | - | - | - | |
| ENST00000523039.1 | IL6ST-010 | 481 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000583149.1 | IL6ST-013 | 479 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000506241.1 | IL6ST-009 | 418 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - |
