Gene: PLCB1 ENSG00000182621

Description

phospholipase C, beta 1 (phosphoinositide-specific) [Source:HGNC Symbol;Acc:15917]

Gene Synonyms

EIEE12, KIAA0581, PI-PLC, PLC-154, PLC-I, PLC154, PLCB1A, PLCB1B

Location

Chromosome 20: 8,112,824-8,949,003 forward strand.

GRCh37:CM000682.1

About this gene

This gene has 9 transcripts (splice variants), 11 paralogues and is associated with 5 phenotypes.

Transcripts

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Transcript ID	Name	bp	Protein	Biotype	CCDS	UniProt Match	RefSeq	Flags
ENST00000338037.6	PLCB1-003	6729	1216aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS13102	Q9NQ66	NM_015192.3	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000378641.3	PLCB1-005	7295	1173aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS13103	Q9NQ66	NM_182734.2	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000378637.2	PLCB1-004	3854	1173aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS13103	Q9NQ66	-	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000439627.1	PLCB1-007	707	196aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding		Q8IV92	-	5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete,
ENST00000404098.2	PLCB1-001	697	232aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding		B1AK73	-	5' and 3' truncations in transcript evidence prevent annotation of the start and the end of the CDS.CDS 5' and 3' incomplete,
ENST00000437439.1	PLCB1-008	288	30aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding		Q8IV91	-	5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete,
ENST00000487210.1	PLCB1-002	4777	914aa	Nonsense mediated decay		-	-	5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete,
ENST00000494924.1	PLCB1-006	2340	No protein	Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript		-	-	-
ENST00000475958.1	PLCB1-009	443	No protein	Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript		-	-	-

Summary

Name

PLCB1 (HGNC Symbol)

UniProtKB

This gene has proteins that correspond to the following UniProtKB identifiers: Q9NQ66

CCDS

This gene is a member of the Human CCDS set: CCDS13102.1, CCDS13103.1

Ensembl version

ENSG00000182621.12

Other assemblies

There is no ungapped mapping of this gene onto the GRCh38 assembly.

Gene type

Protein coding

Annotation method

Annotation for this gene includes both automatic annotation from Ensembl and Havana manual curation, see article.

Alternative genes

This gene corresponds to the following database identifiers:

Havana gene:	OTTHUMG00000031849 (version 7)

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Gene: PLCB1 ENSG00000182621

Summary