Gene: CYP3A4 ENSG00000160868

Description

cytochrome P450, family 3, subfamily A, polypeptide 4 [Source:HGNC Symbol;Acc:2637]

Gene Synonyms

CP33, CP34, CYP3A, CYP3A3, CYPIIIA3, CYPIIIA4, HLP, NF-25, P450C3, P450PCN1

Location

GRCh37:CM000669.1

About this gene

This gene has 4 transcripts (splice variants) and 15 paralogues.

Transcripts

Transcript ID	Name	bp	Protein	Biotype	CCDS	UniProt Match	RefSeq	Flags
ENST00000336411.2	CYP3A4-001	2153	503aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS5674	B4DPQ5 P08684 Q6GRK0 Q7Z448 Q9BZM0	NM_017460.5	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000354593.2	CYP3A4-201	2318	353aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding		B4DPQ5 E7EVM8 Q9BZM0	-	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000415003.1	CYP3A4-003	564	153aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding		C9JBD2	-	3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENST00000480043.1	CYP3A4-002	651	No protein	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-

Summary

Name

CYP3A4 (HGNC Symbol)

UniProtKB

This gene has proteins that correspond to the following UniProtKB identifiers: P08684

CCDS

This gene is a member of the Human CCDS set: CCDS5674.1

Ensembl version

ENSG00000160868.10

Other assemblies

This gene maps to 99,756,981-99,784,265 in GRCh38 coordinates.

Gene type

Protein coding

Annotation method

Annotation for this gene includes both automatic annotation from Ensembl and Havana manual curation, see article.

Alternative genes

This gene corresponds to the following database identifiers:

Havana gene:	OTTHUMG00000156651 (version 1)

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