Description
lymphocyte-specific protein tyrosine kinase [Source:HGNC Symbol;Acc:6524]
Gene Synonyms
LSK, YT16, p56lck, pp58lck
Location
Chromosome 1: 32,716,840-32,751,766 forward strand.
GRCh37:CM000663.1
About this gene
This gene has 13 transcripts (splice variants), 12 paralogues and is associated with 49 phenotypes.
Transcripts
| Transcript ID | Name | bp | Protein | Translation ID | Biotype | CCDS | UniProt Match | RefSeq | Flags |
|---|---|---|---|---|---|---|---|---|---|
| ENST00000336890.5 | LCK-001 | 2117 | 509aa | ENSP00000337825.5 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS359 | B3KUV3 F8W6B9 P06239 | NM_005356.3 | A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000333070.4 | LCK-004 | 2166 | 539aa | ENSP00000328213.4 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | F8W6B9 P06239 | NM_001042771.1 | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, | |
| ENST00000373564.3 | LCK-201 | 1551 | 516aa | ENSP00000362665.3 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | E9PKQ8 E9PQ10 Q573B4 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, | |
| ENST00000495610.2 | LCK-006 | 1060 | 319aa | ENSP00000435605.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | E9PJ92 F8W6B9 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000373557.2 | LCK-010 | 932 | 285aa | ENSP00000362658.2 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | E9PAP0 F8W6B9 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000482949.1 | LCK-002 | 714 | 200aa | ENSP00000431517.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | E9PKQ8 E9PQ10 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000477031.2 | LCK-011 | 580 | 167aa | ENSP00000436554.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | E9PI33 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000461712.2 | LCK-012 | 566 | 149aa | ENSP00000434525.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | E9PQ10 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000373562.3 | LCK-013 | 551 | 137aa | ENSP00000362663.3 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | F8W6B9 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000469765.1 | LCK-007 | 2126 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000469956.1 | LCK-003 | 923 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000355928.3 | LCK-014 | 726 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000476457.1 | LCK-009 | 720 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - |
