Description
serine hydroxymethyltransferase 2 (mitochondrial) [Source:HGNC Symbol;Acc:10852]
Gene Synonyms
GLYA, HEL-S-51e, SHMT
Location
Chromosome 12: 57,623,110-57,628,718 forward strand.
GRCh37:CM000674.1
About this gene
This gene has 36 transcripts (splice variants), 1 paralogue and is associated with 2 phenotypes.
Transcripts
| Transcript ID | Name | bp | Protein | Translation ID | Biotype | CCDS | UniProt Match | RefSeq | Flags |
|---|---|---|---|---|---|---|---|---|---|
| ENST00000328923.3 | SHMT2-001 | 2537 | 504aa | ENSP00000333667.3 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS8934 | G3V241 G3V2W0 G3V2Y4 G3V3Y8 G3V4T0 G3V4X0 G3V5L0 P34897 | NM_005412.5 | A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic, |
| ENST00000449049.3 | SHMT2-008 | 2121 | 483aa | ENSP00000413770.3 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS53805 | G3V241 G3V2W0 G3V2Y4 G3V3Y8 G3V4T0 G3V4X0 G3V5L0 P34897 | NM_001166357.1 | The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic, |
| ENST00000414700.3 | SHMT2-005 | 2006 | 483aa | ENSP00000406881.3 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS53805 | G3V241 G3V2W0 G3V2Y4 G3V3Y8 G3V4T0 G3V4X0 G3V5L0 P34897 | NM_001166358.1 | The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic, |
| ENST00000557487.1 | SHMT2-015 | 1918 | 494aa | ENSP00000452315.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS55837 | G3V241 G3V2W0 G3V3Y8 G3V4T0 G3V4X0 P34897 | - | The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic, |
| ENST00000393827.4 | SHMT2-201 | 1885 | 408aa | ENSP00000377413.4 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | B4DLV4 | - | The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic, | |
| ENST00000553474.1 | SHMT2-009 | 1765 | 483aa | ENSP00000452419.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS53805 | G3V241 G3V2W0 G3V2Y4 G3V3Y8 G3V4T0 G3V4X0 G3V5L0 P34897 | NM_001166359.1 | The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic, |
| ENST00000557529.1 | SHMT2-030 | 1369 | 264aa | ENSP00000450490.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | - | - | 5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete, | |
| ENST00000555634.1 | SHMT2-019 | 964 | 234aa | ENSP00000450930.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | G3V2Y4 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000554975.1 | SHMT2-028 | 780 | 215aa | ENSP00000452404.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | G3V241 G3V2W0 G3V3Y8 G3V4T0 G3V4X0 G3V5L0 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000556689.1 | SHMT2-033 | 768 | 237aa | ENSP00000452035.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | G3V241 G3V2W0 G3V3Y8 G3V4T0 G3V4W5 G3V4X0 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000555773.1 | SHMT2-027 | 600 | 149aa | ENSP00000451968.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | G3V241 G3V3Y8 G3V4T0 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000554310.1 | SHMT2-023 | 579 | 160aa | ENSP00000450893.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | G3V241 G3V2W0 G3V3Y8 G3V4T0 G3V4X0 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000556737.1 | SHMT2-038 | 572 | 147aa | ENSP00000451495.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | G3V241 G3V3Y8 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000557427.1 | SHMT2-025 | 569 | 159aa | ENSP00000452045.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | G3V241 G3V3Y8 G3V4T0 G3V4X0 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000553529.1 | SHMT2-022 | 562 | 147aa | ENSP00000452161.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | G3V241 G3V3Y8 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000557703.1 | SHMT2-021 | 542 | 142aa | ENSP00000450452.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | G3V241 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000555774.1 | SHMT2-012 | 2311 | 65aa | ENSP00000451872.1 | Nonsense mediated decay | G3V2Y1 | - | - | |
| ENST00000556825.1 | SHMT2-004 | 2215 | 86aa | ENSP00000451169.1 | Nonsense mediated decay | G3V2Y1 G3V3C6 | - | - | |
| ENST00000553837.1 | SHMT2-011 | 2152 | 192aa | ENSP00000451371.1 | Nonsense mediated decay | G3V241 G3V2D2 G3V2W0 G3V3Y8 G3V4T0 G3V4X0 G3V540 | - | - | |
| ENST00000557433.1 | SHMT2-013 | 1904 | 171aa | ENSP00000450610.1 | Nonsense mediated decay | G3V241 G3V2E4 G3V3Y8 G3V4T0 | - | - | |
| ENST00000555116.1 | SHMT2-010 | 1885 | 65aa | ENSP00000452339.1 | Nonsense mediated decay | G3V2Y1 | - | - | |
| ENST00000557348.1 | SHMT2-006 | 1659 | 65aa | ENSP00000450927.1 | Nonsense mediated decay | G3V2Y1 | - | - | |
| ENST00000555563.1 | SHMT2-035 | 895 | 86aa | ENSP00000451630.1 | Nonsense mediated decay | G3V2Y1 G3V3C6 | - | - | |
| ENST00000554604.1 | SHMT2-036 | 879 | 192aa | ENSP00000452163.1 | Nonsense mediated decay | G3V241 G3V2D2 G3V2W0 G3V3Y8 G3V4T0 G3V4X0 G3V540 | - | - | |
| ENST00000557269.1 | SHMT2-020 | 576 | 52aa | ENSP00000450594.1 | Nonsense mediated decay | G3V2D2 | - | - | |
| ENST00000554600.1 | SHMT2-034 | 837 | No protein | - | Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript | - | - | - | |
| ENST00000554656.1 | SHMT2-026 | 817 | No protein | - | Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript | - | - | - | |
| ENST00000557740.1 | SHMT2-016 | 569 | No protein | - | Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript | - | - | - | |
| ENST00000553949.1 | SHMT2-037 | 552 | No protein | - | Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript | - | - | - | |
| ENST00000554467.1 | SHMT2-002 | 3416 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000553868.1 | SHMT2-032 | 941 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000555213.1 | SHMT2-031 | 611 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000553950.1 | SHMT2-018 | 584 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000553324.1 | SHMT2-017 | 566 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000556798.1 | SHMT2-029 | 525 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000557302.1 | SHMT2-024 | 457 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - |
