Gene: PDGFB ENSG00000100311

Description

platelet-derived growth factor beta polypeptide [Source:HGNC Symbol;Acc:8800]

Gene Synonyms

IBGC5, PDGF-2, PDGF2, SIS, SSV, c-sis

Location

GRCh37:CM000684.1

About this gene

This gene has 4 transcripts (splice variants), 1 paralogue and is associated with 54 phenotypes.

Transcripts

Transcript ID	Name	bp	Protein	Biotype	CCDS	UniProt Match	RefSeq	Flags
ENST00000331163.6	PDGFB-001	3497	241aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS13987	A9UJN9 A9UJP0 P01127 P78450 Q9UE56 Q9UE57	NM_002608.2	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000381551.4	PDGFB-002	1125	226aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS33650	A9UJN9 A9UJP0 P01127 Q9UE56 Q9UE57	NM_033016.2	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000440375.1	PDGFB-004	556	136aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding		A9UJN9 Q9UE57	-	3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENST00000455790.1	PDGFB-003	554	144aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding		A9UJN9 A9UJP0 Q9UE57	-	3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,

Summary

Name

PDGFB (HGNC Symbol)

UniProtKB

This gene has proteins that correspond to the following UniProtKB identifiers: P01127

CCDS

This gene is a member of the Human CCDS set: CCDS13987.1, CCDS33650.1

Ensembl version

ENSG00000100311.12

Other assemblies

This gene maps to 39,223,359-39,244,751 in GRCh38 coordinates.

Gene type

Protein coding

Annotation method

Annotation for this gene includes both automatic annotation from Ensembl and Havana manual curation, see article.

Alternative genes

This gene corresponds to the following database identifiers:

Havana gene:	OTTHUMG00000151029 (version 14)

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