Description
topoisomerase (DNA) I, mitochondrial [Source:HGNC Symbol;Acc:29787]
Location
Chromosome 8: 144,386,554-144,442,149 reverse strand.
GRCh37:CM000670.1
About this gene
This gene has 19 transcripts (splice variants) and 1 paralogue.
Transcripts
| Transcript ID | Name | bp | Protein | Translation ID | Biotype | CCDS | UniProt Match | RefSeq | Flags |
|---|---|---|---|---|---|---|---|---|---|
| ENST00000329245.4 | TOP1MT-001 | 1958 | 601aa | ENSP00000328835.3 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS6400 | E5KMK7 E5RFS0 E5RJ33 E5RJ95 Q8TBP3 Q969P6 | NM_052963.2 | A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000523676.1 | TOP1MT-005 | 1982 | 503aa | ENSP00000429181.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS59115 | E5RFS0 E5RJ33 E5RJ95 Q8TBP3 Q969P6 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000521193.1 | TOP1MT-003 | 1960 | 503aa | ENSP00000428369.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS59115 | E5RFS0 E5RJ33 E5RJ95 Q8TBP3 Q969P6 | NM_001258446.1 | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000519148.1 | TOP1MT-002 | 1868 | 503aa | ENSP00000429169.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS59115 | E5RFS0 E5RJ33 E5RJ95 Q8TBP3 Q969P6 | NM_001258447.1 | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000519139.2 | TOP1MT-006 | 1561 | 376aa | ENSP00000428451.2 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | E5RFS0 E5RIC7 E5RJ33 E5RJ95 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000519591.1 | TOP1MT-016 | 1007 | 201aa | ENSP00000429177.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | E5RJ33 E5RJ95 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000522041.1 | TOP1MT-017 | 906 | 221aa | ENSP00000427998.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | E5RFS0 E5RJ33 E5RJ95 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000519977.1 | TOP1MT-013 | 892 | 111aa | ENSP00000427925.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | Q8TBP3 | - | 5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete, | |
| ENST00000518760.1 | TOP1MT-020 | 613 | 164aa | ENSP00000428723.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | E5RGR4 E5RJ33 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000520950.1 | TOP1MT-011 | 564 | 33aa | ENSP00000430635.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | E5RJ33 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000518007.1 | TOP1MT-021 | 509 | 134aa | ENSP00000430209.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | E5RGE7 E5RJ33 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000522043.1 | TOP1MT-015 | 499 | 164aa | ENSP00000428931.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | E5RFE3 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000518951.2 | TOP1MT-007 | 1461 | 167aa | ENSP00000428727.1 | Nonsense mediated decay | E5RGR2 E5RJ33 | - | - | |
| ENST00000522121.1 | TOP1MT-018 | 874 | 49aa | ENSP00000430139.1 | Nonsense mediated decay | H0YBR3 | - | 5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete, | |
| ENST00000523417.1 | TOP1MT-019 | 698 | 123aa | ENSP00000430679.1 | Nonsense mediated decay | - | - | 5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete, | |
| ENST00000505857.2 | TOP1MT-004 | 2029 | No protein | - | Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript | - | - | - | |
| ENST00000521024.1 | TOP1MT-010 | 520 | No protein | - | Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript | - | - | - | |
| ENST00000524092.1 | TOP1MT-014 | 313 | No protein | - | Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript | - | - | - | |
| ENST00000517857.1 | TOP1MT-012 | 624 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - |
