Description
proprotein convertase subtilisin/kexin type 7 [Source:HGNC Symbol;Acc:8748]
Gene Synonyms
LPC, PC7, PC8, SPC7
Location
Chromosome 11: 117,075,053-117,103,241 reverse strand.
GRCh37:CM000673.1
About this gene
This gene has 15 transcripts (splice variants) and 6 paralogues.
Transcripts
| Transcript ID | Name | bp | Protein | Translation ID | Biotype | CCDS | UniProt Match | RefSeq | Flags |
|---|---|---|---|---|---|---|---|---|---|
| ENST00000320934.3 | PCSK7-001 | 4649 | 785aa | ENSP00000325917.3 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS8382 | B3KUH2 E9PIW7 E9PLM0 E9PMC0 Q16549 | NM_004716.2 | A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000540028.1 | PCSK7-201 | 3169 | 237aa | ENSP00000441944.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | B3KUH2 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, | |
| ENST00000525027.1 | PCSK7-004 | 1312 | 305aa | ENSP00000431181.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | E9PIW7 E9PLM0 E9PMC0 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000530269.1 | PCSK7-005 | 583 | 91aa | ENSP00000433252.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | E9PLM0 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000524507.1 | PCSK7-007 | 553 | 113aa | ENSP00000433841.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | E9PIW7 E9PLM0 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000532301.1 | PCSK7-006 | 549 | 92aa | ENSP00000436459.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | E9PLM0 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000529458.1 | PCSK7-015 | 695 | No protein | - | Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript | - | - | - | |
| ENST00000533135.1 | PCSK7-010 | 549 | No protein | - | Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript | - | - | - | |
| ENST00000528973.1 | PCSK7-011 | 9347 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000534529.1 | PCSK7-003 | 5393 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000528217.1 | PCSK7-008 | 2954 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000527037.1 | PCSK7-009 | 2346 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000527861.1 | PCSK7-013 | 925 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000532810.1 | PCSK7-012 | 589 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000531573.1 | PCSK7-014 | 562 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - |
