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Summary
- Splice variants
- Transcript comparison
- Gene alleles
Sequence
- Secondary Structure
Comparative Genomics
Ontologies
Phenotypes
Genetic Variation
Gene expression
Pathway
Molecular interactions
Regulation
External references
Supporting evidence
ID History
- Gene history

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Gene: HMGCS1 ENSG00000112972

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Description

3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) [Source:HGNC Symbol;Acc:5007]

Gene Synonyms

HMGCS

Location

Chromosome 5: 43,289,497-43,313,614 reverse strand.

GRCh37:CM000667.1

About this gene

This gene has 7 transcripts (splice variants) and 1 paralogue.

Transcripts

Show transcript tableHide transcript table

Transcript ID	Name	bp	Protein	Translation ID	Biotype	CCDS	UniProt Match	RefSeq	Flags
ENST00000325110.6	HMGCS1-001	3506	520aa	ENSP00000322706.6	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS34154	D6RIW1 Q01581 Q8N995	NM_001098272.2	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000433297.2	HMGCS1-003	3466	520aa	ENSP00000399402.2	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS34154	D6RIW1 Q01581 Q8N995	NM_002130.7	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000511774.1	HMGCS1-004	500	95aa	ENSP00000427339.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		D6RIW1	-	3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENST00000507004.1	HMGCS1-006	950	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-
ENST00000507293.1	HMGCS1-005	708	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-
ENST00000508319.1	HMGCS1-008	591	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-
ENST00000514610.1	HMGCS1-007	555	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-

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Summary

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