Description
polymerase (DNA directed), epsilon, catalytic subunit [Source:HGNC Symbol;Acc:9177]
Gene Synonyms
CRCS12, FILS, POLE1
Location
Chromosome 12: 133,200,348-133,263,951 reverse strand.
GRCh37:CM000674.1
About this gene
This gene has 24 transcripts (splice variants) and is associated with 98 phenotypes.
Transcripts
| Transcript ID | Name | bp | Protein | Translation ID | Biotype | CCDS | UniProt Match | RefSeq | Flags |
|---|---|---|---|---|---|---|---|---|---|
| ENST00000320574.5 | POLE-001 | 7840 | 2286aa | ENSP00000322570.5 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS9278 | D3DXI9 F5H0H8 F5H3W5 F5H5Q5 F5H7H6 Q07864 Q8WU23 Q96IE1 Q9UNE8 | NM_006231.2 | A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000535270.1 | POLE-004 | 6800 | 2259aa | ENSP00000445753.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | D3DXI9 F5H0H8 F5H1D6 F5H3W5 F5H5Q5 F5H7H6 Q8WU23 Q96IE1 Q9UNE8 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, | |
| ENST00000539006.1 | POLE-006 | 3575 | 1163aa | ENSP00000442519.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | F5H0H8 F5H3W5 F5H5Q5 F5H7H6 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000536445.1 | POLE-014 | 2334 | 307aa | ENSP00000439052.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | F5H0H8 F5H3W5 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000535934.1 | POLE-010 | 1561 | 180aa | ENSP00000443213.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | F5H5Q5 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000503265.3 | POLE-016 | 1501 | 123aa | ENSP00000439842.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | F5H0H8 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000537064.1 | POLE-002 | 8011 | 310aa | ENSP00000442578.1 | Nonsense mediated decay | F5H7E4 Q9UNE8 | - | - | |
| ENST00000434528.3 | POLE-027 | 808 | No protein | - | Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript | - | - | - | |
| ENST00000544870.1 | POLE-025 | 659 | No protein | - | Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript | - | - | - | |
| ENST00000441786.2 | POLE-015 | 552 | No protein | - | Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript | - | - | - | |
| ENST00000538196.1 | POLE-026 | 551 | No protein | - | Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript | - | - | - | |
| ENST00000539618.1 | POLE-008 | 299 | No protein | - | Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript | - | - | - | |
| ENST00000544692.1 | POLE-003 | 2221 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000541627.1 | POLE-007 | 2096 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000541213.1 | POLE-020 | 1675 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000534922.1 | POLE-024 | 1660 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000540987.1 | POLE-017 | 587 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000544414.1 | POLE-022 | 575 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000416953.2 | POLE-021 | 542 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000543516.1 | POLE-018 | 535 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000542362.1 | POLE-019 | 508 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000539215.1 | POLE-012 | 483 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000545015.1 | POLE-013 | 366 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000539357.1 | POLE-009 | 364 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - |
