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Summary
- Splice variants
- Transcript comparison
- Gene alleles
Sequence
- Secondary Structure
Comparative Genomics
Ontologies
Phenotypes
Genetic Variation
Gene expression
Pathway
Molecular interactions
Regulation
External references
Supporting evidence
ID History
- Gene history

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Gene: BACE1 ENSG00000186318

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Description

beta-site APP-cleaving enzyme 1 [Source:HGNC Symbol;Acc:933]

Gene Synonyms

ASP2, BACE, HSPC104, KIAA1149

Location

Chromosome 11: 117,156,402-117,186,975 reverse strand.

GRCh37:CM000673.1

About this gene

This gene has 12 transcripts (splice variants) and 9 paralogues.

Transcripts

Show transcript tableHide transcript table

Transcript ID	Name	bp	Protein	Translation ID	Biotype	CCDS	UniProt Match	RefSeq	Flags
ENST00000313005.6	BACE1-001	5847	501aa	ENSP00000318585.6	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS8383	H0YDX0 P56817 U3KPS1	NM_138973.3	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000392937.6	BACE1-006	5155	401aa	ENSP00000475405.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS55787	H0YDX0 P56817 U3KPS1	NM_001207049.1	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000528053.1	BACE1-013	4083	467aa	ENSP00000431848.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		E9PJG7 H0YDX0	-	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000513780.1	BACE1-003	1465	476aa	ENSP00000424536.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS44739	H0YDX0 P56817 U3KPS1	-	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000445823.2	BACE1-004	1408	457aa	ENSP00000403685.2	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS44740	H0YDX0 P56817 U3KPS1	-	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000428381.2	BACE1-002	1333	432aa	ENSP00000402228.2	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS44741	H0YDX0 P56817 U3KPS1	-	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000510630.1	BACE1-007	1236	376aa	ENSP00000422461.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS55786	H0YDX0 P56817 U3KPS1	-	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000504995.1	BACE1-008	611	40aa	ENSP00000434486.2	Gene/transcipt that contains an open reading frame (ORF).Protein coding		H0YDX0	-	3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENST00000510915.1	BACE1-009	561	51aa	ENSP00000475171.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		H0YDX0 U3KPS1	-	3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENST00000514464.1	BACE1-005	517	No protein	-	Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript		-	-	-
ENST00000530824.1	BACE1-016	984	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-
ENST00000509916.1	BACE1-010	593	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-

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Summary

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