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Summary
- Splice variants
- Transcript comparison
- Gene alleles
Sequence
- Secondary Structure
Comparative Genomics
Ontologies
Phenotypes
Genetic Variation
Gene expression
Pathway
Molecular interactions
Regulation
External references
Supporting evidence
ID History
- Gene history

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Gene: ROCK2 ENSG00000134318

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Description

Rho-associated, coiled-coil containing protein kinase 2 [Source:HGNC Symbol;Acc:10252]

Gene Synonyms

KIAA0619, ROCK-II

Location

Chromosome 2: 11,319,887-11,488,456 reverse strand.

GRCh37:CM000664.1

About this gene

This gene has 8 transcripts (splice variants) and 11 paralogues.

Transcripts

Show transcript tableHide transcript table

Transcript ID	Name	bp	Protein	Translation ID	Biotype	CCDS	UniProt Match	RefSeq	Flags
ENST00000315872.6	ROCK2-001	8292	1388aa	ENSP00000317985.6	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS42654	E9PF63 O75116 Q14DU5	NM_004850.3	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000401753.1	ROCK2-006	4017	1145aa	ENSP00000385509.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		E9PF63 Q14DU5	-	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000431087.1	ROCK2-007	729	203aa	ENSP00000395957.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		C9JFJ0	-	3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENST00000261535.3	ROCK2-008	1795	446aa	ENSP00000261535.3	Nonsense mediated decay		D6REE7	-	-
ENST00000462366.1	ROCK2-005	563	No protein	-	Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript		-	-	-
ENST00000484951.1	ROCK2-002	895	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-
ENST00000460262.1	ROCK2-004	597	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-
ENST00000493096.1	ROCK2-003	461	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-

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Summary

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