Gene: HSD11B2 ENSG00000176387

Description

hydroxysteroid (11-beta) dehydrogenase 2 [Source:HGNC Symbol;Acc:5209]

Gene Synonyms

AME, AME1, HSD11K, HSD2, SDR9C3

Location

GRCh37:CM000678.1

About this gene

This gene has 4 transcripts (splice variants), 13 paralogues and is associated with 2 phenotypes.

Transcripts

Transcript ID	Name	bp	Protein	Translation ID	Biotype	CCDS	UniProt Match	RefSeq	Flags
ENST00000326152.5	HSD11B2-001	1900	405aa	ENSP00000316786.5	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS10837	P80365	NM_000196.3	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000566606.1	HSD11B2-003	634	58aa	ENSP00000473429.1	Nonsense mediated decay		R4GN04	-	5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete,
ENST00000567684.2	HSD11B2-002	540	No protein	-	Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript		-	-	-
ENST00000569303.1	HSD11B2-004	578	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-

Summary