Description
WNK lysine deficient protein kinase 1 [Source:HGNC Symbol;Acc:14540]
Gene Synonyms
HSAN2, HSN2, KDP, KIAA0344, PRKWNK1, PSK, p65
Location
Chromosome 12: 861,759-1,020,618 forward strand.
GRCh37:CM000674.1
About this gene
This gene has 21 transcripts (splice variants), 5 paralogues and is associated with 5 phenotypes.
Transcripts
| Transcript ID | Name | bp | Protein | Translation ID | Biotype | CCDS | UniProt Match | RefSeq | Flags |
|---|---|---|---|---|---|---|---|---|---|
| ENST00000315939.6 | WNK1-001 | 10452 | 2382aa | ENSP00000313059.6 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS8506 | Q96CZ6 Q9H4A3 | NM_018979.3 | A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000537687.1 | WNK1-203 | 11232 | 2642aa | ENSP00000444465.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | I3L251 Q96CZ6 Q9H4A3 | NM_213655.4 | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, | |
| ENST00000535572.1 | WNK1-002 | 9886 | 2134aa | ENSP00000441972.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS53731 | F5GWT4 Q96CZ6 | NM_014823.2 | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000530271.2 | WNK1-202 | 8643 | 2880aa | ENSP00000433548.2 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | F5H2M7 I3L251 Q96CZ6 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, | |
| ENST00000340908.4 | WNK1-201 | 8588 | 1975aa | ENSP00000341292.4 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | Q96CZ6 Q9H4A3 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, | |
| ENST00000447667.2 | WNK1-003 | 1902 | 393aa | ENSP00000392542.2 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | F6UYG0 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, | |
| ENST00000574564.1 | WNK1-020 | 1401 | 434aa | ENSP00000460651.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | Q9H4A3 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, | |
| ENST00000535698.1 | WNK1-015 | 736 | 245aa | ENSP00000439552.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | H0YFP5 | - | 5' and 3' truncations in transcript evidence prevent annotation of the start and the end of the CDS.CDS 5' and 3' incomplete, | |
| ENST00000574679.1 | WNK1-019 | 722 | 240aa | ENSP00000459380.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | I3L251 | - | 5' and 3' truncations in transcript evidence prevent annotation of the start and the end of the CDS.CDS 5' and 3' incomplete, | |
| ENST00000544965.1 | WNK1-016 | 653 | 218aa | ENSP00000438313.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | - | - | 5' and 3' truncations in transcript evidence prevent annotation of the start and the end of the CDS.CDS 5' and 3' incomplete, | |
| ENST00000534872.1 | WNK1-008 | 584 | 194aa | ENSP00000446253.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | H0YH68 | - | 5' and 3' truncations in transcript evidence prevent annotation of the start and the end of the CDS.CDS 5' and 3' incomplete, | |
| ENST00000545285.1 | WNK1-006 | 528 | 176aa | ENSP00000446462.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | - | - | 5' and 3' truncations in transcript evidence prevent annotation of the start and the end of the CDS.CDS 5' and 3' incomplete, | |
| ENST00000544559.1 | WNK1-018 | 226 | 76aa | ENSP00000437503.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | - | - | 5' and 3' truncations in transcript evidence prevent annotation of the start and the end of the CDS.CDS 5' and 3' incomplete, | |
| ENST00000543065.1 | WNK1-017 | 201 | 67aa | ENSP00000438985.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | H0YFK5 | - | 5' and 3' truncations in transcript evidence prevent annotation of the start and the end of the CDS.CDS 5' and 3' incomplete, | |
| ENST00000540360.1 | WNK1-004 | 668 | No protein | - | Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript | - | - | - | |
| ENST00000538787.1 | WNK1-005 | 579 | No protein | - | Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript | - | - | - | |
| ENST00000542424.1 | WNK1-014 | 912 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000540885.1 | WNK1-011 | 874 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000545055.1 | WNK1-010 | 624 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000537603.1 | WNK1-013 | 553 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000542543.1 | WNK1-009 | 506 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - |
