Description
protein tyrosine phosphatase, non-receptor type 2 [Source:HGNC Symbol;Acc:9650]
Gene Synonyms
PTN2, PTPT, TC-PTP, TCELLPTP, TCPTP
Location
Chromosome 18: 12,785,477-12,929,642 reverse strand.
GRCh37:CM000680.1
About this gene
This gene has 15 transcripts (splice variants), 13 paralogues and is associated with 4 phenotypes.
Transcripts
| Transcript ID | Name | bp | Protein | Translation ID | Biotype | CCDS | UniProt Match | RefSeq | Flags |
|---|---|---|---|---|---|---|---|---|---|
| ENST00000309660.5 | PTPN2-002 | 3467 | 415aa | ENSP00000311857.3 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS11865 | D3DUJ3 K7ER87 P17706 | NM_002828.3 | A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000591497.1 | PTPN2-005 | 3390 | 386aa | ENSP00000467823.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | D3DUJ3 K7EQG9 Q59F91 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, | |
| ENST00000327283.3 | PTPN2-003 | 1706 | 387aa | ENSP00000320298.3 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS11863 | A8K3N4 K7ER87 P17706 | NM_080422.2 | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000591115.1 | PTPN2-004 | 1648 | 410aa | ENSP00000466936.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS59306 | K7ENG3 K7ER87 | NM_001207013.1 | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000353319.4 | PTPN2-001 | 1542 | 353aa | ENSP00000320546.3 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS11864 | K7ER87 P17706 | NM_080423.2 | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000585666.1 | PTPN2-014 | 812 | 151aa | ENSP00000464719.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | - | - | 5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete, | |
| ENST00000591901.1 | PTPN2-015 | 743 | 112aa | ENSP00000464937.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | - | - | 5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete, | |
| ENST00000587703.1 | PTPN2-012 | 577 | 146aa | ENSP00000467043.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | - | - | 5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete, | |
| ENST00000592059.1 | PTPN2-011 | 577 | 68aa | ENSP00000466206.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | K7ELS9 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000591305.1 | PTPN2-007 | 876 | 42aa | ENSP00000468012.1 | Nonsense mediated decay | K7ERU1 | - | - | |
| ENST00000592776.1 | PTPN2-010 | 772 | 165aa | ENSP00000468155.1 | Nonsense mediated decay | K7ER87 | - | - | |
| ENST00000589216.1 | PTPN2-008 | 646 | 42aa | ENSP00000468408.1 | Nonsense mediated decay | K7ERU1 | - | - | |
| ENST00000589086.1 | PTPN2-009 | 549 | No protein | - | Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript | - | - | - | |
| ENST00000587497.1 | PTPN2-013 | 426 | No protein | - | Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript | - | - | - | |
| ENST00000589444.1 | PTPN2-006 | 2264 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - |
