Gene: MMP14 ENSG00000157227

Description

matrix metallopeptidase 14 (membrane-inserted) [Source:HGNC Symbol;Acc:7160]

Gene Synonyms

MMP-14, MMP-X1, MT-MMP, MT-MMP 1, MT1-MMP, MT1MMP, MTMMP1, WNCHRS

Location

Chromosome 14: 23,305,766-23,318,236 forward strand.

GRCh37:CM000676.1

About this gene

This gene has 6 transcripts (splice variants), 14 paralogues and is associated with 3 phenotypes.

Transcripts

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Transcript ID	Name	bp	Protein	Translation ID	Biotype	CCDS	UniProt Match	RefSeq	Flags
ENST00000311852.6	MMP14-001	3732	582aa	ENSP00000308208.6	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS9577	P50281	NM_004995.3	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000548761.1	MMP14-007	582	194aa	ENSP00000446989.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		F8W1B7	-	3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENST00000547279.1	MMP14-006	412	71aa	ENSP00000450323.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		F8VP90	-	3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENST00000548162.1	MMP14-003	1740	No protein	-	Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript		-	-	-
ENST00000547596.1	MMP14-008	575	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-
ENST00000547074.1	MMP14-005	560	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-

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Gene: MMP14 ENSG00000157227

Summary