Description
leucine rich transmembrane and O-methyltransferase domain containing [Source:HGNC Symbol;Acc:25033]
Gene Synonyms
COMT2, DFNB63, LRRC51, TOMT
Location
Chromosome 11: 71,791,382-71,821,828 forward strand.
GRCh37:CM000673.1
About this gene
This gene has 22 transcripts (splice variants), 1 paralogue and is associated with 2 phenotypes.
Transcripts
| Transcript ID | Name | bp | Protein | Translation ID | Biotype | CCDS | UniProt Match | RefSeq | Flags |
|---|---|---|---|---|---|---|---|---|---|
| ENST00000435085.1 | LRTOMT-203 | 3822 | 291aa | ENSP00000409789.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS44668 | Q8WZ04 | NM_001145309.3 | A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000419228.1 | LRTOMT-202 | 3705 | 251aa | ENSP00000392233.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | Q8WZ04 | NM_001145310.3 | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, | |
| ENST00000307198.7 | LRTOMT-201 | 3601 | 291aa | ENSP00000305742.7 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS44668 | Q8WZ04 | NM_001145308.4 | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000324866.7 | LRTOMT-006 | 2402 | 146aa | ENSP00000440693.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS59227 | F5GYI0 F5H0M6 Q96E66 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000289488.2 | LRTOMT-001 | 2332 | 192aa | ENSP00000289488.2 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS8208 | B0AZV1 F5GYI0 F5H0M6 Q96E66 | NM_145309.5 | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000423494.2 | LRTOMT-003 | 1270 | 174aa | ENSP00000441249.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS55778 | B0AZV1 Q96E66 | NM_001205138.3 | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000447974.1 | LRTOMT-204 | 983 | 158aa | ENSP00000414271.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS44667 | F5GYI0 F5H0M6 Q96E66 | NM_001145307.4 | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000538413.1 | LRTOMT-011 | 842 | 92aa | ENSP00000438762.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | F5H0M6 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000538478.1 | LRTOMT-014 | 814 | 192aa | ENSP00000444583.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS8208 | B0AZV1 F5GYI0 F5H0M6 Q96E66 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000439209.1 | LRTOMT-002 | 801 | 156aa | ENSP00000395139.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | C9JDG7 F5GYI0 F5H0M6 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, | |
| ENST00000541614.1 | LRTOMT-010 | 726 | 158aa | ENSP00000438522.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS44667 | F5GYI0 F5H0M6 Q96E66 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000536917.1 | LRTOMT-016 | 579 | 146aa | ENSP00000443421.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS59227 | F5GYI0 F5H0M6 Q96E66 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000539271.1 | LRTOMT-012 | 570 | 43aa | ENSP00000442267.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | F5H6F7 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, | |
| ENST00000542846.1 | LRTOMT-015 | 527 | 103aa | ENSP00000440248.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | F5GYI0 F5H0M6 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000539587.1 | LRTOMT-004 | 428 | 43aa | ENSP00000437649.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | F5H6F7 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, | |
| ENST00000537483.1 | LRTOMT-018 | 308 | 65aa | ENSP00000437985.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | F5H614 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000440313.2 | LRTOMT-020 | 253 | 47aa | ENSP00000390485.2 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | F8WBA5 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, | |
| ENST00000427369.2 | LRTOMT-008 | 3299 | 227aa | ENSP00000409403.2 | Nonsense mediated decay | F5GYI0 F5H0M6 Q96E66 | - | - | |
| ENST00000544409.1 | LRTOMT-007 | 3182 | 187aa | ENSP00000440969.1 | Nonsense mediated decay | F5GYI0 F5H0M6 Q96E66 | - | - | |
| ENST00000535883.1 | LRTOMT-009 | 1263 | 38aa | ENSP00000437561.1 | Nonsense mediated decay | F5H6K5 | - | - | |
| ENST00000412777.2 | LRTOMT-013 | 548 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000541899.1 | LRTOMT-019 | 540 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - |
