Gene: MAP2K1 ENSG00000169032

Description

mitogen-activated protein kinase kinase 1 [Source:HGNC Symbol;Acc:6840]

Gene Synonyms

CFC3, MAPKK1, MEK1, MKK1, PRKMK1

Location

GRCh37:CM000677.1

About this gene

This gene has 3 transcripts (splice variants), 6 paralogues and is associated with 66 phenotypes.

Transcripts

Transcript ID	Name	bp	Protein	Translation ID	Biotype	CCDS	UniProt Match	RefSeq	Flags
ENST00000307102.5	MAP2K1-001	3410	393aa	ENSP00000302486.4	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS10216	A4QPA9 Q02750	NM_002755.3	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000566326.1	MAP2K1-003	1432	217aa	ENSP00000456438.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		H3BRW9	-	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000425818.2	MAP2K1-002	1338	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-

Summary