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Summary
- Splice variants
- Transcript comparison
- Gene alleles
Sequence
- Secondary Structure
Comparative Genomics
- Paralogues
- Genomic alignments
- Gene tree
- Gene gain/loss tree
- Orthologues
Ontologies
Phenotypes
Genetic Variation
Gene expression
Pathway
Molecular interactions
Regulation
External references
Supporting evidence
ID History
- Gene history

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Gene: TPP1 ENSG00000166340

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Description

tripeptidyl peptidase I [Source:HGNC Symbol;Acc:2073]

Gene Synonyms

CLN2, LPIC, TPP-1

Location

Chromosome 11: 6,634,000-6,640,692 reverse strand.

GRCh37:CM000673.1

About this gene

This gene has 16 transcripts (splice variants) and is associated with 6 phenotypes.

Transcripts

Show transcript tableHide transcript table

Transcript ID	Name	bp	Protein	Translation ID	Biotype	CCDS	UniProt Match	RefSeq	Flags
ENST00000299427.6	TPP1-001	3530	563aa	ENSP00000299427.6	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS7770	D3DQU2 E9PME9 O14773	NM_000391.3	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000533371.1	TPP1-003	3536	320aa	ENSP00000437066.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		O14773	-	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000528657.1	TPP1-008	578	30aa	ENSP00000435001.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		E9PME9	-	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000436873.2	TPP1-019	560	177aa	ENSP00000398136.2	Gene/transcipt that contains an open reading frame (ORF).Protein coding		E7EV34 E9PME9	-	3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENST00000528571.1	TPP1-017	561	39aa	ENSP00000434647.1	Nonsense mediated decay		E9PME9 E9PPA4	-	-
ENST00000534644.1	TPP1-016	636	No protein	-	Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript		-	-	-
ENST00000528807.1	TPP1-018	585	No protein	-	Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript		-	-	-
ENST00000524903.1	TPP1-011	556	No protein	-	Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript		-	-	-
ENST00000524788.1	TPP1-015	553	No protein	-	Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript		-	-	-
ENST00000530040.1	TPP1-010	551	No protein	-	Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript		-	-	-
ENST00000524611.1	TPP1-012	470	No protein	-	Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript		-	-	-
ENST00000532191.1	TPP1-014	433	No protein	-	Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript		-	-	-
ENST00000524924.1	TPP1-013	289	No protein	-	Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript		-	-	-
ENST00000428886.2	TPP1-002	841	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-
ENST00000531754.1	TPP1-007	610	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-
ENST00000528917.1	TPP1-009	559	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-

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Summary

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