Description
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta [Source:HGNC Symbol;Acc:8976]
Gene Synonyms
P110BETA, PI3K, PI3KBETA, PIK3C1
Location
Chromosome 3: 138,372,860-138,553,780 reverse strand.
GRCh37:CM000665.1
About this gene
This gene has 14 transcripts (splice variants), 7 paralogues and is associated with 64 phenotypes.
Transcripts
| Transcript ID | Name | bp | Protein | Translation ID | Biotype | CCDS | UniProt Match | RefSeq | Flags |
|---|---|---|---|---|---|---|---|---|---|
| ENST00000477593.1 | PIK3CB-001 | 4658 | 1070aa | ENSP00000418143.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS3104 | C9J345 C9JNF6 C9JYX0 P42338 Q6PJ60 Q9BTS4 | - | A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000289153.2 | PIK3CB-201 | 3213 | 1070aa | ENSP00000289153.2 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS3104 | C9J345 C9JNF6 C9JYX0 P42338 Q6PJ60 Q9BTS4 | NM_006219.2 | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000544716.1 | PIK3CB-202 | 3181 | 521aa | ENSP00000438259.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | Q68DL0 Q6PJ60 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, | |
| ENST00000493568.1 | PIK3CB-004 | 2347 | 702aa | ENSP00000417869.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | B4DZI3 Q6PJ60 Q9BTS4 | - | 5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete, | |
| ENST00000483968.1 | PIK3CB-007 | 721 | 131aa | ENSP00000419857.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | C9J345 C9JNF6 C9JYX0 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000465581.1 | PIK3CB-008 | 690 | 56aa | ENSP00000417329.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | C9J345 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000461451.1 | PIK3CB-003 | 667 | 100aa | ENSP00000420399.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | C9J345 C9JNF6 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000462294.1 | PIK3CB-014 | 542 | 181aa | ENSP00000418834.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | - | - | 5' and 3' truncations in transcript evidence prevent annotation of the start and the end of the CDS.CDS 5' and 3' incomplete, | |
| ENST00000462898.1 | PIK3CB-002 | 4747 | 134aa | ENSP00000420108.1 | Nonsense mediated decay | C9J345 C9JNF6 C9JYX0 F8WDJ8 | - | - | |
| ENST00000469284.2 | PIK3CB-005 | 3164 | 34aa | ENSP00000419513.2 | Nonsense mediated decay | H7C5C3 | - | 5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete, | |
| ENST00000473435.1 | PIK3CB-009 | 904 | 245aa | ENSP00000419091.1 | Nonsense mediated decay | H7C565 | - | 5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete, | |
| ENST00000481749.1 | PIK3CB-006 | 2396 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000485060.1 | PIK3CB-010 | 612 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000487552.1 | PIK3CB-012 | 581 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - |
