Description
aldo-keto reductase family 1, member B1 (aldose reductase) [Source:HGNC Symbol;Acc:381]
Gene Synonyms
ADR, ALDR1, ALR2, AR
Location
Chromosome 7: 134,127,102-134,144,036 reverse strand.
GRCh37:CM000669.1
About this gene
This gene has 14 transcripts (splice variants) and 10 paralogues.
Transcripts
| Transcript ID | Name | bp | Protein | Translation ID | Biotype | CCDS | UniProt Match | RefSeq | Flags |
|---|---|---|---|---|---|---|---|---|---|
| ENST00000285930.4 | AKR1B1-001 | 1409 | 316aa | ENSP00000285930.3 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS5831 | O15289 P15121 | NM_001628.2 | A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000434222.1 | AKR1B1-002 | 1852 | 263aa | ENSP00000414399.1 | Nonsense mediated decay | E9PCX2 O15289 Q59EL5 | - | - | |
| ENST00000426422.1 | AKR1B1-009 | 521 | 102aa | ENSP00000413205.1 | Nonsense mediated decay | E9PEF9 O15289 | - | - | |
| ENST00000489022.1 | AKR1B1-014 | 577 | No protein | - | Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript | - | - | - | |
| ENST00000487438.1 | AKR1B1-005 | 557 | No protein | - | Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript | - | - | - | |
| ENST00000497983.1 | AKR1B1-013 | 534 | No protein | - | Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript | - | - | - | |
| ENST00000465351.1 | AKR1B1-003 | 1930 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000491741.1 | AKR1B1-004 | 1188 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000498771.1 | AKR1B1-010 | 858 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000467251.1 | AKR1B1-015 | 723 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000484592.1 | AKR1B1-011 | 639 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000462784.1 | AKR1B1-007 | 598 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000467829.1 | AKR1B1-006 | 561 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000498373.1 | AKR1B1-012 | 549 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - |
