Description
p21 protein (Cdc42/Rac)-activated kinase 1 [Source:HGNC Symbol;Acc:8590]
Gene Synonyms
PAKalpha
Location
Chromosome 11: 77,032,752-77,185,680 reverse strand.
GRCh37:CM000673.1
About this gene
This gene has 20 transcripts (splice variants), 5 paralogues and is associated with 2 phenotypes.
Transcripts
| Transcript ID | Name | bp | Protein | Translation ID | Biotype | CCDS | UniProt Match | RefSeq | Flags |
|---|---|---|---|---|---|---|---|---|---|
| ENST00000278568.4 | PAK1-002 | 2543 | 553aa | ENSP00000278568.4 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS44687 | E9PJF8 E9PKH9 E9PM17 E9PMP2 E9PQW5 E9PRP6 Q13153 | NM_001128620.1 | A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000356341.3 | PAK1-001 | 3737 | 545aa | ENSP00000348696.3 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS8250 | B7Z302 E9PJF8 E9PKH9 E9PMP2 E9PQW5 E9PRP6 Q13153 | NM_002576.4 | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000530617.1 | PAK1-003 | 3001 | 522aa | ENSP00000433423.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | B3KNX7 E9PJF8 E9PKH9 E9PMP2 E9PQW5 E9PRP6 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, | |
| ENST00000528203.1 | PAK1-004 | 1878 | 455aa | ENSP00000433211.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | E9PM17 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, | |
| ENST00000533285.1 | PAK1-018 | 878 | 244aa | ENSP00000431541.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | - | - | 5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete, | |
| ENST00000528592.1 | PAK1-011 | 581 | 89aa | ENSP00000433004.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | E9PJF8 E9PMP2 E9PRP6 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000529248.1 | PAK1-009 | 576 | 106aa | ENSP00000433518.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | E9PJF8 E9PKH9 E9PMP2 E9PQW5 E9PRP6 | - | - | |
| ENST00000524847.1 | PAK1-007 | 559 | 99aa | ENSP00000432477.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | E9PJF8 E9PMP2 E9PQW5 E9PRP6 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000526968.1 | PAK1-006 | 502 | 26aa | ENSP00000433737.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | E9PJF8 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000528633.1 | PAK1-010 | 450 | 63aa | ENSP00000435983.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | E9PJF8 E9PRP6 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000527457.1 | PAK1-014 | 1047 | 167aa | ENSP00000431906.1 | Nonsense mediated decay | - | - | 5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete, | |
| ENST00000527535.1 | PAK1-019 | 576 | 18aa | ENSP00000437261.1 | Nonsense mediated decay | - | - | 5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete, | |
| ENST00000525542.1 | PAK1-005 | 863 | No protein | - | Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript | - | - | - | |
| ENST00000532991.1 | PAK1-017 | 806 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000533568.1 | PAK1-008 | 762 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000526103.1 | PAK1-016 | 753 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000530358.1 | PAK1-015 | 735 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000533468.1 | PAK1-013 | 503 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000526910.1 | PAK1-012 | 348 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000532711.1 | PAK1-020 | 308 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - |
