Description
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2 [Source:HGNC Symbol;Acc:3430]
Gene Synonyms
CD340, HER-2, HER-2/neu, HER2, MLN 19, MLN19, NEU, NGL, TKR1
Location
Chromosome 17: 37,844,167-37,886,679 forward strand.
GRCh37:CM000679.1
About this gene
This gene has 24 transcripts (splice variants), 13 paralogues and is associated with 101 phenotypes.
Transcripts
| Transcript ID | Name | bp | Protein | Translation ID | Biotype | CCDS | UniProt Match | RefSeq | Flags |
|---|---|---|---|---|---|---|---|---|---|
| ENST00000269571.5 | ERBB2-008 | 4545 | 1255aa | ENSP00000269571.4 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS32642 | F5H1T4 J3KS21 J3QLV2 P04626 Q9NP09 | - | A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000406381.2 | ERBB2-201 | 4806 | 1225aa | ENSP00000385185.2 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS45667 | F5H1T4 J3KS21 J3QLV2 Q9NP09 | NM_001005862.1 | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000584601.1 | ERBB2-001 | 4792 | 1225aa | ENSP00000462438.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS45667 | F5H1T4 J3KS21 J3QLV2 Q9NP09 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000540147.1 | ERBB2-203 | 4624 | 1225aa | ENSP00000443562.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS45667 | F5H1T4 J3KS21 J3QLV2 Q9NP09 | NM_004448.2 | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000541774.1 | ERBB2-204 | 4341 | 1240aa | ENSP00000446466.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | F5H1T4 J3KS21 J3QLV2 P04626 Q9NP09 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, | |
| ENST00000584450.1 | ERBB2-005 | 3730 | 1055aa | ENSP00000463714.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | F5H1T4 J3KS21 J3QLU9 J3QLV2 Q9NP09 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, | |
| ENST00000445658.2 | ERBB2-004 | 3238 | 979aa | ENSP00000404047.2 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | B4DTR1 Q9NP09 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, | |
| ENST00000578199.1 | ERBB2-003 | 2526 | 603aa | ENSP00000462808.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | F5H1T4 J3KS21 J3QLV2 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, | |
| ENST00000540042.1 | ERBB2-202 | 2147 | 603aa | ENSP00000446382.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | F5H1T4 J3KS21 J3QLV2 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, | |
| ENST00000580074.1 | ERBB2-018 | 754 | 251aa | ENSP00000463002.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | Q9NP09 | - | 5' and 3' truncations in transcript evidence prevent annotation of the start and the end of the CDS.CDS 5' and 3' incomplete, | |
| ENST00000584099.1 | ERBB2-013 | 583 | 139aa | ENSP00000462270.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | J3KS21 J3QLV2 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000578709.1 | ERBB2-012 | 559 | 102aa | ENSP00000463719.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | J3QLV2 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000582818.1 | ERBB2-019 | 529 | 177aa | ENSP00000464252.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | Q9NP09 | - | 5' and 3' truncations in transcript evidence prevent annotation of the start and the end of the CDS.CDS 5' and 3' incomplete, | |
| ENST00000578502.1 | ERBB2-015 | 497 | 166aa | ENSP00000464420.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | - | - | 5' and 3' truncations in transcript evidence prevent annotation of the start and the end of the CDS.CDS 5' and 3' incomplete, | |
| ENST00000578373.1 | ERBB2-007 | 4523 | 90aa | ENSP00000463427.1 | Nonsense mediated decay | J3QL83 | - | - | |
| ENST00000582648.1 | ERBB2-011 | 1013 | 96aa | ENSP00000462024.1 | Nonsense mediated decay | J3KRI9 | - | - | |
| ENST00000584888.1 | ERBB2-020 | 500 | No protein | - | Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript | - | - | - | |
| ENST00000583038.1 | ERBB2-010 | 4930 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000582788.1 | ERBB2-006 | 2004 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000584908.1 | ERBB2-009 | 1316 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000578630.1 | ERBB2-016 | 874 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000584014.1 | ERBB2-002 | 849 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000584684.1 | ERBB2-017 | 649 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000583391.1 | ERBB2-014 | 465 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - |
