Gene: LGR5 ENSG00000139292

Description

leucine-rich repeat containing G protein-coupled receptor 5 [Source:HGNC Symbol;Acc:4504]

Gene Synonyms

FEX, GPR49, GPR67, GRP49, HG38

Location

Chromosome 12: 71,833,550-71,980,090 forward strand.

GRCh37:CM000674.1

About this gene

This gene has 6 transcripts (splice variants) and 7 paralogues.

Transcripts

Show transcript tableHide transcript table

Transcript ID	Name	bp	Protein	Biotype	CCDS	UniProt Match	RefSeq	Flags
ENST00000266674.5	LGR5-001	4611	907aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS9000	O75473	NM_003667.3	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000540815.2	LGR5-004	2800	883aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS61194	O75473	-	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000536515.1	LGR5-003	2664	835aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS61195	D8MCT0	-	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000550851.1	LGR5-002	4095	No protein	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-
ENST00000547310.1	LGR5-005	576	No protein	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-
ENST00000549015.1	LGR5-006	298	No protein	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-

Summary

Name

LGR5 (HGNC Symbol)

UniProtKB

This gene has proteins that correspond to the following UniProtKB identifiers: O75473

CCDS

This gene is a member of the Human CCDS set: CCDS61194.1, CCDS61195.1, CCDS9000.1

Ensembl version

ENSG00000139292.8

Other assemblies

This gene maps to 71,439,770-71,586,310 in GRCh38 coordinates.

Gene type

Protein coding

Annotation method

Annotation for this gene includes both automatic annotation from Ensembl and Havana manual curation, see article.

Alternative genes

This gene corresponds to the following database identifiers:

Havana gene:	OTTHUMG00000169543 (version 1)

Loading component

Favourite species

All species

Recent locations

Gene: LGR5 ENSG00000139292

Summary