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Summary
- Splice variants
- Transcript comparison
- Gene alleles
Sequence
- Secondary Structure
Comparative Genomics
Ontologies
Phenotypes
Genetic Variation
Gene expression
Pathway
Molecular interactions
Regulation
External references
Supporting evidence
ID History
- Gene history

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Gene: IDE ENSG00000119912

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Description

insulin-degrading enzyme [Source:HGNC Symbol;Acc:5381]

Gene Synonyms

INSULYSIN

Location

Chromosome 10: 94,211,441-94,333,833 reverse strand.

GRCh37:CM000672.1

About this gene

This gene has 8 transcripts (splice variants) and 1 paralogue.

Transcripts

Show transcript tableHide transcript table

Transcript ID	Name	bp	Protein	Translation ID	Biotype	CCDS	UniProt Match	RefSeq	Flags
ENST00000265986.6	IDE-001	5877	1019aa	ENSP00000265986.6	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS7421	P14735	NM_004969.3	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000371581.5	IDE-201	4480	464aa	ENSP00000360637.5	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS53554	P14735	NM_001165946.1	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000436178.1	IDE-007	772	257aa	ENSP00000408850.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		Q5T5N3	-	5' and 3' truncations in transcript evidence prevent annotation of the start and the end of the CDS.CDS 5' and 3' incomplete,
ENST00000478361.2	IDE-002	3198	61aa	ENSP00000473506.1	Nonsense mediated decay		R4GN65	-	-
ENST00000496903.1	IDE-003	1867	No protein	-	Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript		-	-	-
ENST00000492362.1	IDE-006	747	No protein	-	Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript		-	-	-
ENST00000463640.1	IDE-005	506	No protein	-	Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript		-	-	-
ENST00000462988.1	IDE-004	482	No protein	-	Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript		-	-	-

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Summary

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