Gene: ABCB11 ENSG00000073734

Description

ATP-binding cassette, sub-family B (MDR/TAP), member 11 [Source:HGNC Symbol;Acc:42]

Gene Synonyms

ABC16, BRIC2, BSEP, PFIC-2, PFIC2, PGY4, SPGP

Location

GRCh37:CM000664.1

View alleles of this gene on alternative sequences

About this gene

This gene has 3 transcripts (splice variants), 1 gene allele, 3 paralogues and is associated with 7 phenotypes.

Transcripts

Transcript ID	Name	bp	Protein	Translation ID	Biotype	CCDS	UniProt Match	RefSeq	Flags
ENST00000263817.6	ABCB11-001	4775	1321aa	ENSP00000263817.6	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS46444	B4DYQ0 O95342 Q53S60 Q9UIL3	NM_003742.2	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000439188.1	ABCB11-003	2822	72aa	ENSP00000416058.1	Nonsense mediated decay		H7C486	-	5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete,
ENST00000478354.1	ABCB11-004	576	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-

Summary