Gene: NOX4 ENSG00000086991

Description

NADPH oxidase 4 [Source:HGNC Symbol;Acc:7891]

Gene Synonyms

KOX, KOX-1, RENOX

Location

Chromosome 11: 89,057,524-89,322,779 reverse strand.

GRCh37:CM000673.1

About this gene

This gene has 18 transcripts (splice variants) and 6 paralogues.

Transcripts

Show transcript tableHide transcript table

Transcript ID	Name	bp	Protein	Biotype	CCDS	UniProt Match	RefSeq	Flags
ENST00000263317.4	NOX4-001	2388	578aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS8285	E7EMD7 Q9NPH5	-	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000535633.1	NOX4-203	4376	554aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS44696	E7EMD7	NM_016931.3	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000424319.1	NOX4-202	4184	554aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS44696	E7EMD7	-	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000343727.5	NOX4-005	3347	554aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS44696	E7EMD7	-	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000542487.1	NOX4-204	2610	554aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS44696	E7EMD7	NM_001143837.1	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000527956.1	NOX4-002	2379	554aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS44696	E7EMD7	-	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000534731.1	NOX4-013	2156	538aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS44695	E9PMY6 Q9NPH5	-	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000532825.1	NOX4-004	2039	514aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding		E9PMY6	-	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000528341.1	NOX4-006	1899	553aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding		E9PPP2	-	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000413594.2	NOX4-201	1825	599aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding		C9J897 E7EMD7	-	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000527626.1	NOX4-007	1774	391aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding		E9PR43	-	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000525196.1	NOX4-008	1555	342aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding		E9PI95	-	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000375979.3	NOX4-009	816	271aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding		Q9NPH5	-	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000531342.1	NOX4-010	696	231aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding		Q9NPH5	-	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000393282.2	NOX4-003	560	54aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding		Q9NPH5	-	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000529343.1	NOX4-012	1403	224aa	Nonsense mediated decay		Q9NPH5	-	-
ENST00000525278.1	NOX4-011	1309	No protein	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-
ENST00000524473.1	NOX4-014	755	No protein	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-

Summary

Name

NOX4 (HGNC Symbol)

UniProtKB

This gene has proteins that correspond to the following UniProtKB identifiers: Q9NPH5

CCDS

This gene is a member of the Human CCDS set: CCDS44695.1, CCDS44696.1, CCDS8285.1

Ensembl version

ENSG00000086991.8

Other assemblies

This gene maps to 89,324,356-89,589,611 in GRCh38 coordinates.

Gene type

Protein coding

Annotation method

Annotation for this gene includes both automatic annotation from Ensembl and Havana manual curation, see article.

Alternative genes

This gene corresponds to the following database identifiers:

Havana gene:	OTTHUMG00000167298 (version 1)

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Gene: NOX4 ENSG00000086991

Summary