Gene: MAP3K8 ENSG00000107968

Description

mitogen-activated protein kinase kinase kinase 8 [Source:HGNC Symbol;Acc:6860]

Gene Synonyms

COT, EST, ESTF, MEKK8, TPL2, Tpl-2, c-COT

Location

Chromosome 10: 30,722,866-30,750,762 forward strand.

GRCh37:CM000672.1

About this gene

This gene has 7 transcripts (splice variants) and 7 paralogues.

Transcripts

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Transcript ID	Name	bp	Protein	Biotype	CCDS	UniProt Match	RefSeq	Flags
ENST00000263056.1	MAP3K8-002	3096	467aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS7166	P41279 Q5T853 Q5T857	NM_005204.3	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000375321.1	MAP3K8-003	2518	467aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS7166	P41279 Q5T853 Q5T857	-	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000542547.1	MAP3K8-201	1682	467aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS7166	P41279 Q5T853 Q5T857	-	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000415139.1	MAP3K8-004	1026	255aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding		Q5T853 Q5T857	-	3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENST00000375322.2	MAP3K8-006	932	132aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding		Q5T854	-	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000413724.1	MAP3K8-005	776	223aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding		Q5T853	-	3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENST00000430603.1	MAP3K8-001	647	No protein	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-

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Gene: MAP3K8 ENSG00000107968

Summary