Gene: HSD11B1 ENSG00000117594

Description

hydroxysteroid (11-beta) dehydrogenase 1 [Source:HGNC Symbol;Acc:5208]

Gene Synonyms

11-DH, 11-beta-HSD1, CORTRD2, HDL, HSD11, HSD11B, HSD11L, SDR26C1

Location

GRCh37:CM000663.1

About this gene

This gene has 3 transcripts (splice variants), 1 paralogue and is associated with 2 phenotypes.

Transcripts

Transcript ID	Name	bp	Protein	Biotype	CCDS	UniProt Match	RefSeq	Flags
ENST00000367028.2	HSD11B1-002	1477	292aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS1489	P28845	NM_001206741.1	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000261465.1	HSD11B1-201	1415	292aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS1489	P28845	NM_181755.2	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000367027.3	HSD11B1-001	1319	292aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS1489	P28845	NM_005525.3	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,

Summary

Name

HSD11B1 (HGNC Symbol)

UniProtKB

This gene has proteins that correspond to the following UniProtKB identifiers: P28845

CCDS

This gene is a member of the Human CCDS set: CCDS1489.1

Ensembl version

ENSG00000117594.5

Other assemblies

This gene maps to 209,686,165-209,734,950 in GRCh38 coordinates.

Gene type

Protein coding

Annotation method

Annotation for this gene includes both automatic annotation from Ensembl and Havana manual curation, see article.

Alternative genes

This gene corresponds to the following database identifiers:

Havana gene:	OTTHUMG00000036481 (version 2)

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