Gene: LRP6 ENSG00000070018

Description

low density lipoprotein receptor-related protein 6 [Source:HGNC Symbol;Acc:6698]

Gene Synonyms

ADCAD2

Location

Chromosome 12: 12,268,959-12,419,946 reverse strand.

GRCh37:CM000674.1

About this gene

This gene has 7 transcripts (splice variants), 12 paralogues and is associated with 5 phenotypes.

Transcripts

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Transcript ID	Name	bp	Protein	Translation ID	Biotype	CCDS	UniProt Match	RefSeq	Flags
ENST00000261349.4	LRP6-001	10020	1613aa	ENSP00000261349.4	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS8647	B3KQA9 F5H0Z3 O75581	NM_002336.2	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000543091.1	LRP6-004	4774	1568aa	ENSP00000442472.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		F5H0Z3 F5H7J9	-	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000540527.1	LRP6-006	593	69aa	ENSP00000443239.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		H0YGH0	-	5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete,
ENST00000535731.1	LRP6-002	562	75aa	ENSP00000439765.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		F5H0Z3	-	3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENST00000538239.1	LRP6-003	7812	1478aa	ENSP00000445083.1	Nonsense mediated decay		B3KQA9 F5H0Z3	-	5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete,
ENST00000540415.1	LRP6-005	473	No protein	-	Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript		-	-	-
ENST00000545658.1	LRP6-007	435	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-

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Gene: LRP6 ENSG00000070018

Summary