Description
cyclin-dependent kinase 4 [Source:HGNC Symbol;Acc:1773]
Gene Synonyms
CMM3, PSK-J3
Location
Chromosome 12: 58,141,510-58,149,796 reverse strand.
GRCh37:CM000674.1
About this gene
This gene has 16 transcripts (splice variants), 4 paralogues and is associated with 47 phenotypes.
Transcripts
| Transcript ID | Name | bp | Protein | Translation ID | Biotype | CCDS | UniProt Match | RefSeq | Flags |
|---|---|---|---|---|---|---|---|---|---|
| ENST00000257904.6 | CDK4-001 | 2076 | 303aa | ENSP00000257904.5 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS8953 | B4DNF9 F8VWX7 F8VXD2 F8VYH9 F8VZ13 F8VZ51 F8VZZ0 F8W1L8 P11802 Q6LC83 | NM_000075.3 | A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000312990.6 | CDK4-201 | 1000 | 111aa | ENSP00000316889.6 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | Q96BE9 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, | |
| ENST00000540325.1 | CDK4-202 | 952 | 183aa | ENSP00000439076.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | B4DNF9 F8VZ13 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, | |
| ENST00000547281.1 | CDK4-009 | 825 | 186aa | ENSP00000447274.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | F8VXD2 F8VZZ0 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000546489.1 | CDK4-007 | 776 | 208aa | ENSP00000447779.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | F8VXD2 F8VZ51 F8VZZ0 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000551800.1 | CDK4-005 | 773 | 132aa | ENSP00000449391.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | F8VXD2 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000552254.1 | CDK4-011 | 769 | 203aa | ENSP00000449179.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | F8VWX7 F8VYH9 F8W1L8 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000552388.1 | CDK4-006 | 694 | 170aa | ENSP00000448963.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | F8VYH9 F8W1L8 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000549606.1 | CDK4-004 | 558 | 40aa | ENSP00000447005.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | F8VZ13 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, | |
| ENST00000552862.1 | CDK4-012 | 447 | 115aa | ENSP00000446763.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | F8W1L8 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000547853.1 | CDK4-010 | 228 | 2aa | ENSP00000449725.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | - | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000553237.1 | CDK4-003 | 952 | 74aa | ENSP00000448885.1 | Nonsense mediated decay | F8VYY1 | - | - | |
| ENST00000550419.1 | CDK4-008 | 919 | 201aa | ENSP00000448098.1 | Nonsense mediated decay | F8VTV8 F8VYH9 F8W1L8 | - | - | |
| ENST00000551888.1 | CDK4-013 | 636 | No protein | - | Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript | - | - | - | |
| ENST00000551706.1 | CDK4-002 | 984 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000552713.1 | CDK4-014 | 685 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - |
