Gene: ALOX12 ENSG00000108839

Description

arachidonate 12-lipoxygenase [Source:HGNC Symbol;Acc:429]

Gene Synonyms

12-LOX, 12LO, 12S-LOX, LOG12

Location

GRCh37:CM000679.1

About this gene

This gene has 3 transcripts (splice variants), 5 paralogues and is associated with 2 phenotypes.

Transcripts

Transcript ID	Name	bp	Protein	Biotype	CCDS	UniProt Match	RefSeq	Flags
ENST00000251535.6	ALOX12-001	2358	663aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS11084	P18054	NM_000697.2	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000480801.1	ALOX12-003	443	147aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding		K7ENN9	-	5' and 3' truncations in transcript evidence prevent annotation of the start and the end of the CDS.CDS 5' and 3' incomplete,
ENST00000406228.1	ALOX12-002	1023	No protein	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-

Summary

Name

ALOX12 (HGNC Symbol)

UniProtKB

This gene has proteins that correspond to the following UniProtKB identifiers: P18054

CCDS

This gene is a member of the Human CCDS set: CCDS11084.1

Ensembl version

ENSG00000108839.7

Other assemblies

This gene maps to 6,996,065-7,010,736 in GRCh38 coordinates.

Gene type

Protein coding

Annotation method

Annotation for this gene includes both automatic annotation from Ensembl and Havana manual curation, see article.

Alternative genes

This gene corresponds to the following database identifiers:

Havana gene:	OTTHUMG00000102088 (version 4)

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