Description
sirtuin 2 [Source:HGNC Symbol;Acc:10886]
Gene Synonyms
SIR2, SIR2L, SIR2L2
Location
Chromosome 19: 39,369,197-39,390,502 reverse strand.
GRCh37:CM000681.1
About this gene
This gene has 18 transcripts (splice variants) and 1 paralogue.
Transcripts
| Transcript ID | Name | bp | Protein | Translation ID | Biotype | CCDS | UniProt Match | RefSeq | Flags |
|---|---|---|---|---|---|---|---|---|---|
| ENST00000249396.7 | SIRT2-001 | 2070 | 389aa | ENSP00000249396.7 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS12523 | B5MCS1 C9J3U7 C9JR33 C9JZQ0 E7EWX6 F8WF57 Q8IXJ6 | NM_012237.3 | A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000392081.2 | SIRT2-002 | 2062 | 352aa | ENSP00000375931.2 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS46069 | B5MCS1 C9J3U7 C9JR33 C9JZQ0 E7EWX6 F8WF57 Q8IXJ6 | NM_030593.2 | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000358931.5 | SIRT2-201 | 1784 | 271aa | ENSP00000351809.5 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | B5MCS1 C9J3U7 C9JR33 C9JZQ0 F8WF57 Q8IXJ6 | NM_001193286.1 | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, | |
| ENST00000414941.1 | SIRT2-008 | 1251 | 237aa | ENSP00000404309.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | B5MCS1 C9J3U7 C9JR33 C9JZQ0 E7EWX6 F8WF57 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000407552.1 | SIRT2-005 | 890 | 169aa | ENSP00000385146.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | B5MCS1 C9J3U7 C9JR33 C9JZQ0 F8WF57 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000381766.4 | SIRT2-016 | 848 | 130aa | ENSP00000401203.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | C9J3U7 C9JR33 C9JZQ0 F8WF57 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000447739.1 | SIRT2-006 | 578 | 73aa | ENSP00000408023.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | C9JR33 F8WF57 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000437828.1 | SIRT2-007 | 555 | 78aa | ENSP00000397022.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | C9J3U7 C9JR33 F8WF57 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000443898.1 | SIRT2-009 | 985 | 96aa | ENSP00000411393.1 | Nonsense mediated decay | F8WBT6 | - | - | |
| ENST00000420440.1 | SIRT2-010 | 927 | 111aa | ENSP00000400338.1 | Nonsense mediated decay | C9J3U7 C9JR33 F8WCF4 F8WF57 | - | - | |
| ENST00000451193.1 | SIRT2-011 | 556 | 39aa | ENSP00000407272.1 | Nonsense mediated decay | F8WF57 | - | - | |
| ENST00000423526.1 | SIRT2-012 | 556 | 52aa | ENSP00000409690.1 | Nonsense mediated decay | F8WDM4 | - | - | |
| ENST00000481381.1 | SIRT2-015 | 618 | No protein | - | Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript | - | - | - | |
| ENST00000479290.1 | SIRT2-004 | 4734 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000462654.1 | SIRT2-003 | 2539 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000491960.1 | SIRT2-014 | 619 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000496069.1 | SIRT2-017 | 606 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000476771.1 | SIRT2-013 | 584 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - |
