Description
protein C (inactivator of coagulation factors Va and VIIIa) [Source:HGNC Symbol;Acc:9451]
Gene Synonyms
APC, PC, PROC1, THPH3, THPH4
Location
Chromosome 2: 128,176,003-128,186,822 forward strand.
GRCh37:CM000664.1
About this gene
This gene has 12 transcripts (splice variants), 12 paralogues and is associated with 4 phenotypes.
Transcripts
| Transcript ID | Name | bp | Protein | Translation ID | Biotype | CCDS | UniProt Match | RefSeq | Flags |
|---|---|---|---|---|---|---|---|---|---|
| ENST00000234071.3 | PROC-001 | 1773 | 461aa | ENSP00000234071.3 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS2145 | B4DPC8 E7EU72 E7EVH6 P04070 Q6V7X9 Q8J003 Q8J004 | NM_000312.3 | A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000453608.2 | PROC-202 | 1853 | 516aa | ENSP00000404030.2 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | B4DPC8 B4DPQ7 E7END6 E7EU72 E7EVH6 Q6V7X9 Q8J003 Q8J004 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, | |
| ENST00000409048.1 | PROC-002 | 1586 | 495aa | ENSP00000386679.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | B4DPC8 E7END6 E7EU72 E7EVH6 Q6V7X9 Q8J003 Q8J004 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, | |
| ENST00000422777.3 | PROC-201 | 1386 | 461aa | ENSP00000409543.3 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS2145 | B4DPC8 E7EU72 E7EVH6 P04070 Q6V7X9 Q8J003 Q8J004 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000402125.2 | PROC-012 | 779 | 236aa | ENSP00000384225.2 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | Q6V7X9 | - | 5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete, | |
| ENST00000442644.1 | PROC-010 | 600 | 175aa | ENSP00000411241.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | E7ENR9 E7EU72 E7EVH6 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000427769.1 | PROC-006 | 598 | 116aa | ENSP00000406295.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | E7EU72 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000429925.1 | PROC-003 | 581 | 126aa | ENSP00000412697.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | E7EU72 E7EVH6 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000431364.1 | PROC-007 | 566 | 52aa | ENSP00000391220.1 | Nonsense mediated decay | F2Z2A0 | - | - | |
| ENST00000419985.1 | PROC-008 | 500 | 52aa | ENSP00000392606.1 | Nonsense mediated decay | F2Z2A0 | - | - | |
| ENST00000464089.1 | PROC-011 | 563 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000474030.1 | PROC-004 | 501 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - |
