Gene: ACTA2 ENSG00000107796

Description

actin, alpha 2, smooth muscle, aorta [Source:HGNC Symbol;Acc:130]

Gene Synonyms

AAT6, ACTSA, ACTVS, MYMY5

Location

Chromosome 10: 90,694,831-90,751,147 reverse strand.

GRCh37:CM000672.1

About this gene

This gene has 7 transcripts (splice variants), 11 paralogues and is associated with 9 phenotypes.

Transcripts

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Transcript ID	Name	bp	Protein	Biotype	CCDS	UniProt Match	RefSeq	Flags
ENST00000458208.1	ACTA2-201	1756	377aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS7392	B3KPP5 B4DUI8 D2JYH4 F6QUT6 F6UVQ4 P62736 Q562S2	NM_001141945.1	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000224784.6	ACTA2-001	1349	377aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS7392	B3KPP5 B4DUI8 D2JYH4 F6QUT6 F6UVQ4 P62736 Q562S2	NM_001613.2	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000415557.1	ACTA2-002	878	151aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding		F6QUT6 F6UVQ4	-	3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENST00000458159.1	ACTA2-003	744	151aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding		F6QUT6 F6UVQ4	-	3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENST00000480297.1	ACTA2-006	884	No protein	Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript		-	-	-
ENST00000488967.1	ACTA2-005	762	No protein	Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript		-	-	-
ENST00000482085.1	ACTA2-004	755	No protein	Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript		-	-	-

Summary

Name

ACTA2 (HGNC Symbol)

UniProtKB

This gene has proteins that correspond to the following UniProtKB identifiers: P62736

CCDS

This gene is a member of the Human CCDS set: CCDS7392.1

Ensembl version

ENSG00000107796.8

Other assemblies

This gene maps to 88,935,074-88,991,390 in GRCh38 coordinates.

Gene type

Protein coding

Annotation method

Annotation for this gene includes both automatic annotation from Ensembl and Havana manual curation, see article.

Alternative genes

This gene corresponds to the following database identifiers:

Havana gene:	OTTHUMG00000018700 (version 2)

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Gene: ACTA2 ENSG00000107796

Summary