Gene: GZMB ENSG00000100453

Description

granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) [Source:HGNC Symbol;Acc:4709]

Gene Synonyms

CCPI, CGL-1, CGL1, CSP-B, CSPB, CTLA1, CTSGL1, GRB, HLP, SECT

Location

Chromosome 14: 25,100,160-25,103,473 reverse strand.

GRCh37:CM000676.1

About this gene

This gene has 8 transcripts (splice variants) and 11 paralogues.

Transcripts

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Transcript ID	Name	bp	Protein	Translation ID	Biotype	CCDS	UniProt Match	RefSeq	Flags
ENST00000216341.4	GZMB-001	968	247aa	ENSP00000216341.4	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS9633	P10144	-	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000382542.1	GZMB-202	951	281aa	ENSP00000371982.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		J3KPK2	-	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000415355.3	GZMB-003	923	235aa	ENSP00000387385.3	Gene/transcipt that contains an open reading frame (ORF).Protein coding		J3KQ52	NM_004131.4	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000526004.1	GZMB-005	819	90aa	ENSP00000434213.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		E9PRD7	-	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000382540.1	GZMB-201	816	202aa	ENSP00000371980.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		E7EUV0	-	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000530830.1	GZMB-006	772	44aa	ENSP00000435084.1	Nonsense mediated decay		E9PLX4	-	-
ENST00000554242.1	GZMB-007	665	90aa	ENSP00000450535.1	Nonsense mediated decay		E9PRD7	-	-
ENST00000532263.1	GZMB-004	517	35aa	ENSP00000432074.1	Nonsense mediated decay		E9PID1	-	-

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Gene: GZMB ENSG00000100453

Summary