Gene: MAPK1 ENSG00000100030

Description

mitogen-activated protein kinase 1 [Source:HGNC Symbol;Acc:6871]

Gene Synonyms

ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk

Location

GRCh37:CM000684.1

About this gene

This gene has 4 transcripts (splice variants), 6 paralogues and is associated with 55 phenotypes.

Transcripts

Transcript ID	Name	bp	Protein	Biotype	CCDS	UniProt Match	RefSeq	Flags
ENST00000215832.6	MAPK1-001	11022	360aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS13795	B4DHN0 P28482 Q1HBJ4	NM_002745.4	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000398822.3	MAPK1-002	1487	360aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS13795	B4DHN0 P28482 Q1HBJ4	NM_138957.2	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000544786.1	MAPK1-201	951	316aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding		P28482	-	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000491588.1	MAPK1-003	491	No protein	Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript		-	-	-

Summary

Name

MAPK1 (HGNC Symbol)

UniProtKB

This gene has proteins that correspond to the following UniProtKB identifiers: P28482

CCDS

This gene is a member of the Human CCDS set: CCDS13795.1

Ensembl version

ENSG00000100030.10

Other assemblies

There is no ungapped mapping of this gene onto the GRCh38 assembly.

Gene type

Protein coding

Annotation method

Annotation for this gene includes both automatic annotation from Ensembl and Havana manual curation, see article.

Alternative genes

This gene corresponds to the following database identifiers:

Havana gene:	OTTHUMG00000030508 (version 2)

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