Loading…

Summary
- Splice variants
- Transcript comparison
- Gene alleles
Sequence
- Secondary Structure
Comparative Genomics
Ontologies
- GO: Anatomical entity
Phenotypes
Genetic Variation
Gene expression
Pathway
Molecular interactions
External references
Supporting evidence
ID History
- Gene history

Configure this page

Share this page

Bookmark this page

.

Gene: SIRT1 ENSG00000096717

.

Description

sirtuin 1 [Source:HGNC Symbol;Acc:14929]

Gene Synonyms

SIR2L1

Location

Chromosome 10: 69,644,427-69,678,147 forward strand.

GRCh37:CM000672.1

About this gene

This gene has 6 transcripts (splice variants), 157 orthologues and 6 paralogues.

Transcripts

Show transcript tableHide transcript table

Transcript ID	Name	bp	Protein	Translation ID	Biotype	CCDS	UniProt Match	RefSeq	Flags
ENST00000212015.6	SIRT1-001	4094	747aa	ENSP00000212015.6	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS7273	A8K128 E9PC49 Q96EB6	NM_012238.4	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000432464.1	SIRT1-201	3587	452aa	ENSP00000409208.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS44412	E9PC49	NM_001142498.1	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000403579.1	SIRT1-003	3333	444aa	ENSP00000384063.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		B0QZ35	-	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000406900.1	SIRT1-002	3295	444aa	ENSP00000384508.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		B0QZ35	-	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000497639.1	SIRT1-005	673	No protein	-	Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript		-	-	-
ENST00000473922.1	SIRT1-004	576	No protein	-	Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript		-	-	-

.

Summary

.

.