Gene: GPX4 ENSG00000167468

Description

glutathione peroxidase 4 [Source:HGNC Symbol;Acc:4556]

Gene Synonyms

GPx-4, GSHPx-4, MCSP, PHGPx, snGPx, snPHGPx

Location

Chromosome 19: 1,103,936-1,106,787 forward strand.

GRCh37:CM000681.1

About this gene

This gene has 9 transcripts (splice variants), 7 paralogues and is associated with 3 phenotypes.

Transcripts

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Transcript ID	Name	bp	Protein	Translation ID	Biotype	CCDS	UniProt Match	RefSeq	Flags
ENST00000354171.8	GPX4-002	908	197aa	ENSP00000346103.7	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS42457	P36969 Q6PJX4	NM_002085.3	The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic,
ENST00000589115.1	GPX4-011	820	180aa	ENSP00000466872.2	Gene/transcipt that contains an open reading frame (ORF).Protein coding		-	-	The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic,
ENST00000588919.1	GPX4-003	803	260aa	ENSP00000464989.2	Gene/transcipt that contains an open reading frame (ORF).Protein coding		-	-	5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete,
ENST00000585362.2	GPX4-004	754	145aa	ENSP00000473614.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		-	-	3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENST00000593032.1	GPX4-006	582	194aa	ENSP00000465828.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		-	-	5' and 3' truncations in transcript evidence prevent annotation of the start and the end of the CDS.CDS 5' and 3' incomplete,
ENST00000587648.1	GPX4-009	577	155aa	ENSP00000468349.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		-	-	3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENST00000585480.1	GPX4-010	501	166aa	ENSP00000467900.1	Non stop decay		-	-	5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete,
ENST00000592940.1	GPX4-005	1159	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-
ENST00000587932.1	GPX4-012	264	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-

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Gene: GPX4 ENSG00000167468

Summary