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Summary
- Splice variants
- Transcript comparison
- Gene alleles
Sequence
- Secondary Structure
Comparative Genomics
- Paralogues
- Genomic alignments
- Gene tree
- Gene gain/loss tree
- Orthologues
Ontologies
- GO: Anatomical entity
Phenotypes
Genetic Variation
Gene expression
Pathway
Molecular interactions
External references
Supporting evidence
ID History
- Gene history

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Gene: METTL3 ENSG00000165819

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Description

methyltransferase like 3 [Source:HGNC Symbol;Acc:17563]

Gene Synonyms

IME4, M6A, MT-A70, MTA70, Spo8

Location

Chromosome 14: 21,966,277-21,979,517 reverse strand.

GRCh37:CM000676.1

About this gene

This gene has 15 transcripts (splice variants) and 191 orthologues.

Transcripts

Show transcript tableHide transcript table

Transcript ID	Name	bp	Protein	Translation ID	Biotype	CCDS	UniProt Match	RefSeq	Flags
ENST00000298717.4	METTL3-001	2015	580aa	ENSP00000298717.3	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS32044	B3KSH0 Q86U44	NM_019852.3	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000538267.1	METTL3-201	925	153aa	ENSP00000442316.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		B4E349	-	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000377543.3	METTL3-016	563	9aa	ENSP00000366766.3	Gene/transcipt that contains an open reading frame (ORF).Protein coding		-	-	3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENST00000543235.1	METTL3-006	2124	258aa	ENSP00000445523.1	Nonsense mediated decay		B4DTN4	-	-
ENST00000537163.1	METTL3-003	2030	153aa	ENSP00000442407.1	Nonsense mediated decay		B4E349	-	-
ENST00000544248.1	METTL3-004	1570	245aa	ENSP00000437692.1	Nonsense mediated decay		F5H6D8	-	-
ENST00000539760.1	METTL3-010	1462	336aa	ENSP00000440598.1	Nonsense mediated decay		-	-	5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete,
ENST00000545319.1	METTL3-013	563	No protein	-	Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript		-	-	-
ENST00000367606.3	METTL3-014	560	No protein	-	Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript		-	-	-
ENST00000545788.1	METTL3-012	545	No protein	-	Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript		-	-	-
ENST00000396522.2	METTL3-008	2523	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-
ENST00000544500.1	METTL3-009	1789	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-
ENST00000536201.1	METTL3-002	1592	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-
ENST00000539910.1	METTL3-007	1555	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-
ENST00000542054.1	METTL3-011	975	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-

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Summary

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