Description
TBC1 domain containing kinase [Source:HGNC Symbol;Acc:28261]
Gene Synonyms
HSPC302, MGC16169, TBCK, TBCKL
Location
Chromosome 4: 106,962,756-107,242,652 reverse strand.
GRCh37:CM000666.1
About this gene
This gene has 20 transcripts (splice variants), 202 orthologues, 45 paralogues and is associated with 3 phenotypes.
Transcripts
| Transcript ID | Name | bp | Protein | Translation ID | Biotype | CCDS | UniProt Match | RefSeq | Flags |
|---|---|---|---|---|---|---|---|---|---|
| ENST00000273980.5 | TBCK-001 | 8101 | 893aa | ENSP00000273980.4 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS54788 | D6R950 D6RC61 D6RDG2 D6RDY5 Q8TEA7 | - | A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000432496.2 | TBCK-201 | 3362 | 893aa | ENSP00000405847.2 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS54788 | D6R950 D6RC61 D6RDG2 D6RDY5 Q8TEA7 | NM_001163436.1 | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000394706.3 | TBCK-003 | 3349 | 854aa | ENSP00000378196.3 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS54789 | D6R950 D6RC61 D6RDG2 D6RDY5 Q8TEA7 | NM_001163437.1 | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000361687.4 | TBCK-002 | 3312 | 830aa | ENSP00000355338.4 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS3673 | D6R950 D6RC61 Q8TEA7 | NM_033115.3 | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000394708.2 | TBCK-006 | 3047 | 893aa | ENSP00000378198.2 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS54788 | D6R950 D6RC61 D6RDG2 D6RDY5 Q8TEA7 | NM_001163435.1 | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000509532.1 | TBCK-019 | 848 | 159aa | ENSP00000420985.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | D6R950 D6RDG2 D6RDY5 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000503516.1 | TBCK-013 | 601 | 56aa | ENSP00000423834.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | D6RC61 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000509862.1 | TBCK-008 | 600 | 105aa | ENSP00000425197.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | D6R950 D6RDY5 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000507696.1 | TBCK-009 | 579 | 68aa | ENSP00000423637.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | D6R950 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000467183.2 | TBCK-004 | 3566 | 153aa | ENSP00000421182.1 | Nonsense mediated decay | D6R950 D6RDY5 Q5HYF5 | - | - | |
| ENST00000508666.1 | TBCK-012 | 897 | 139aa | ENSP00000422160.1 | Nonsense mediated decay | - | - | 5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete, | |
| ENST00000503832.1 | TBCK-011 | 865 | 85aa | ENSP00000423092.1 | Nonsense mediated decay | - | - | 5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete, | |
| ENST00000505574.1 | TBCK-010 | 282 | 24aa | ENSP00000426093.1 | Nonsense mediated decay | - | - | 5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete, | |
| ENST00000514689.1 | TBCK-015 | 703 | No protein | - | Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript | - | - | - | |
| ENST00000506615.1 | TBCK-017 | 593 | No protein | - | Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript | - | - | - | |
| ENST00000515705.1 | TBCK-014 | 592 | No protein | - | Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript | - | - | - | |
| ENST00000506384.1 | TBCK-018 | 564 | No protein | - | Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript | - | - | - | |
| ENST00000511011.1 | TBCK-016 | 560 | No protein | - | Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript | - | - | - | |
| ENST00000506280.1 | TBCK-005 | 532 | No protein | - | Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript | - | - | - | |
| ENST00000510927.1 | TBCK-007 | 2826 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - |
