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Summary
- Splice variants
- Transcript comparison
- Gene alleles
Sequence
- Secondary Structure
Comparative Genomics
Ontologies
Phenotypes
Genetic Variation
Gene expression
Pathway
Molecular interactions
Regulation
External references
Supporting evidence
ID History
- Gene history

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Gene: TOP2A ENSG00000131747

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Description

topoisomerase (DNA) II alpha 170kDa [Source:HGNC Symbol;Acc:11989]

Gene Synonyms

TOP2, TP2A

Location

Chromosome 17: 38,544,768-38,574,202 reverse strand.

GRCh37:CM000679.1

About this gene

This gene has 5 transcripts (splice variants), 1 paralogue and is associated with 1 phenotype.

Transcripts

Show transcript tableHide transcript table

Transcript ID	Name	bp	Protein	Translation ID	Biotype	CCDS	UniProt Match	RefSeq	Flags
ENST00000423485.1	TOP2A-001	5758	1531aa	ENSP00000411532.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS45672	J3KTB7 J3QR57 P11388	NM_001067.3	The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic,
ENST00000581055.1	TOP2A-003	579	147aa	ENSP00000462908.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		J3KTB7	-	3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENST00000577541.1	TOP2A-006	420	27aa	ENSP00000464055.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		J3QR57	-	5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete,
ENST00000578412.1	TOP2A-005	882	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-
ENST00000577706.1	TOP2A-004	554	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-

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Summary

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