Description
mutL homolog 3 [Source:HGNC Symbol;Acc:7128]
Gene Synonyms
HNPCC7, MLH3
Location
Chromosome 14: 75,480,467-75,518,235 reverse strand.
GRCh37:CM000676.1
About this gene
This gene has 15 transcripts (splice variants), 209 orthologues, 3 paralogues and is associated with 3 phenotypes.
Transcripts
| Transcript ID | Name | bp | Protein | Translation ID | Biotype | CCDS | UniProt Match | RefSeq | Flags |
|---|---|---|---|---|---|---|---|---|---|
| ENST00000355774.2 | MLH3-201 | 7896 | 1453aa | ENSP00000348020.2 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS32123 | G3V384 G3V3E0 H0YJA3 Q9UHC1 | NM_001040108.1 | A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000380968.2 | MLH3-202 | 7872 | 391aa | ENSP00000370355.2 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | Q9Y6S7 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, | |
| ENST00000238662.7 | MLH3-001 | 5233 | 1429aa | ENSP00000238662.7 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS9837 | G3V384 G3V3E0 H0YJA3 Q6PIC9 Q9UHC1 | NM_014381.2 | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000556740.1 | MLH3-003 | 4491 | 1453aa | ENSP00000452316.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS32123 | G3V384 G3V3E0 H0YJA3 Q9UHC1 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000556257.1 | MLH3-002 | 4229 | 1275aa | ENSP00000451540.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | G3V384 G3V3E0 G3V419 H0YJA3 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, | |
| ENST00000553713.1 | MLH3-004 | 2118 | 477aa | ENSP00000451130.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | H0YJA3 | - | 5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete, | |
| ENST00000544985.1 | MLH3-203 | 1119 | 198aa | ENSP00000441371.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | B7Z5D1 H0YJ15 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, | |
| ENST00000553263.1 | MLH3-006 | 616 | 162aa | ENSP00000451192.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | G3V384 G3V3E0 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000557648.1 | MLH3-007 | 583 | 106aa | ENSP00000451095.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | G3V384 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000555144.1 | MLH3-005 | 1120 | 199aa | ENSP00000450647.1 | Nonsense mediated decay | B7Z5D1 | - | 5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete, | |
| ENST00000554697.1 | MLH3-010 | 825 | 124aa | ENSP00000451055.1 | Nonsense mediated decay | H0YJA3 | - | 5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete, | |
| ENST00000556453.1 | MLH3-012 | 635 | 107aa | ENSP00000452136.1 | Nonsense mediated decay | - | - | 5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete, | |
| ENST00000555671.1 | MLH3-011 | 931 | No protein | - | Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript | - | - | - | |
| ENST00000555499.1 | MLH3-008 | 527 | No protein | - | Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript | - | - | - | |
| ENST00000555415.1 | MLH3-009 | 700 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - |
