Description
amyloid beta (A4) precursor-like protein 1 [Source:HGNC Symbol;Acc:597]
Gene Synonyms
APLP
Location
Chromosome 19: 36,358,801-36,370,693 forward strand.
GRCh37:CM000681.1
About this gene
This gene has 11 transcripts (splice variants), 186 orthologues and 2 paralogues.
Transcripts
| Transcript ID | Name | bp | Protein | Translation ID | Biotype | CCDS | UniProt Match | RefSeq | Flags |
|---|---|---|---|---|---|---|---|---|---|
| ENST00000221891.4 | APLP1-002 | 2495 | 651aa | ENSP00000221891.3 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS32997 | A4UCT6 K7ELK0 K7EQJ4 P51693 | NM_005166.3 | A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000537454.2 | APLP1-001 | 2266 | 611aa | ENSP00000441501.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | F5GZ08 K7ELK0 K7EQJ4 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, | |
| ENST00000586861.1 | APLP1-003 | 2052 | 644aa | ENSP00000465694.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | B7Z4G8 K7ELK0 K7EQJ4 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, | |
| ENST00000592316.1 | APLP1-011 | 1324 | 294aa | ENSP00000467854.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | K7ELK0 K7EQJ4 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000587274.1 | APLP1-009 | 1179 | 289aa | ENSP00000474762.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | - | - | 5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete, | |
| ENST00000588808.1 | APLP1-005 | 664 | 221aa | ENSP00000466576.2 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | - | - | 5' and 3' truncations in transcript evidence prevent annotation of the start and the end of the CDS.CDS 5' and 3' incomplete, | |
| ENST00000589743.1 | APLP1-008 | 586 | 173aa | ENSP00000466116.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | K7ELK0 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000590561.1 | APLP1-004 | 2295 | 118aa | ENSP00000466623.1 | Nonsense mediated decay | K7EMS1 | - | - | |
| ENST00000589298.2 | APLP1-007 | 547 | No protein | - | Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript | - | - | - | |
| ENST00000591165.1 | APLP1-012 | 463 | No protein | - | Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript | - | - | - | |
| ENST00000590926.1 | APLP1-006 | 310 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - |
