Description
topoisomerase (DNA) II beta 180kDa [Source:HGNC Symbol;Acc:11990]
Gene Synonyms
TOPIIB, top2beta
Location
Chromosome 3: 25,639,475-25,706,398 reverse strand.
GRCh37:CM000665.1
About this gene
This gene has 9 transcripts (splice variants), 208 orthologues, 1 paralogue and is associated with 1 phenotype.
Transcripts
| Transcript ID | Name | bp | Protein | Translation ID | Biotype | CCDS | UniProt Match | RefSeq | Flags |
|---|---|---|---|---|---|---|---|---|---|
| ENST00000435706.2 | TOP2B-001 | 5389 | 1621aa | ENSP00000396704.2 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS46776 | B4DLV2 E9PCY5 Q02880 Q6LC06 Q8WTY5 | NM_001068.3 | A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000264331.4 | TOP2B-201 | 5189 | 1626aa | ENSP00000264331.4 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | B4DLV2 Q02880 Q6LBI8 Q6LC06 Q8WTY5 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, | |
| ENST00000424225.1 | TOP2B-002 | 3525 | 1150aa | ENSP00000391112.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | E9PCY5 Q6LC06 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000542520.1 | TOP2B-203 | 2061 | 478aa | ENSP00000446023.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | B4DLV2 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, | |
| ENST00000540199.1 | TOP2B-202 | 1897 | 478aa | ENSP00000437352.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | B4DLV2 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, | |
| ENST00000413971.1 | TOP2B-005 | 2049 | 70aa | ENSP00000388216.1 | Nonsense mediated decay | H7BZ82 | - | 5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete, | |
| ENST00000475717.1 | TOP2B-008 | 540 | No protein | - | Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript | - | - | - | |
| ENST00000491510.1 | TOP2B-006 | 584 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000470132.1 | TOP2B-007 | 451 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - |
