Description
major histocompatibility complex, class I, B [Source:HGNC Symbol;Acc:4932]
Gene Synonyms
AS, HLA-B59, HLA-DNA, HLA-DRB1, HLAB, MICA, SPDA1
Location
Chromosome HSCHR6_MHC_SSTO: 31,314,550-31,317,907 reverse strand.
GRCh37:GL000256.1
View this gene on the primary assembly.
About this gene
This gene has 8 transcripts (splice variants), 1 gene allele and is associated with 2 phenotypes.
Transcripts
| Transcript ID | Name | bp | Protein | Translation ID | Biotype | CCDS | UniProt Match | RefSeq | Flags |
|---|---|---|---|---|---|---|---|---|---|
| ENST00000421349.2 | HLA-B-001 | 1589 | 362aa | ENSP00000405365.2 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | A8KNJ4 B3W6N3 C7E565 C8CAY1 C9WCW5 C9WEP5 D1G104 D2DL02 D3JTA5 D3U4A4 D3XDF2 D5FHX4 D5FHY3 D5FHZ4 D5FZL0 D5FZL7 D5H3J5 D7NPN8 D7R0T8 D9U3H2 E0X600 E0YTL0 E2D5R1 E2GJJ4 E2GJJ5 E2GJK4 E2GJL7 E2GJM1 E3SG96 E3SGA2 E7BYA8 E7EDN6 E9LY43 E9LY52 E9LY54 E9LY55 E9LY57 F2VNK6 F2VNM2 F2X5W7 F4YU37 F4YU41 F4YZT7 F6KRS6 F6KRU3 F8R147 F8R164 F8R166 F8R185 G0LXY9 G0WVB8 G0WVB9 G0X8R9 G0ZDT3 G0ZDU1 G0ZDU4 G1ENG0 G1EPI8 G3D6J0 H6A2E1 I1W1M6 I2GUK4 I6NWI4 I7DB68 L7PEX1 L7YDJ5 M1FUS0 P30481 Q000J7 Q29843 Q29923 Q58P05 Q5QR31 Q5QR33 Q5QR34 Q5QR45 Q5QR70 Q5QR71 Q5QR74 Q5QR78 Q66WL2 Q710M7 Q710M8 Q7YNW9 Q861E5 Q8HWR2 Q8HWR3 Q8HWR4 Q8HWR8 Q95HA7 Q95IF2 Q9BD04 Q9GIL2 Q9GIZ8 Q9MY59 Q9MY96 Q9UIM8 R4I3H0 R4I4E4 R5AJZ3 | - | A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, | |
| ENST00000437265.1 | HLA-B-006 | 1154 | 241aa | ENSP00000398100.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | Q29843 Q5QR31 Q5QR33 Q5QR34 Q5QR45 Q710M7 Q710M8 Q861E5 Q95HA7 | - | 5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete, | |
| ENST00000445610.1 | HLA-B-003 | 738 | 246aa | ENSP00000396397.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | C7E565 C8CAY1 C9WCW5 C9WEP5 D1G104 D2DL02 D3JTA5 D3U4A4 D3XDF2 D5FHX4 D5FHY3 D5FHZ4 D5FZL0 D5FZL7 D7NPN8 D7R0T8 D9U3H2 E0X600 E0YTL0 E2D5R1 E2GJJ4 E2GJJ5 E2GJK4 E2GJL7 E2GJM1 E3SG96 E3SGA2 E7BYA8 E7EDN6 E9LY43 E9LY52 E9LY54 E9LY55 E9LY57 F2VNK6 F2VNM2 F2X5W7 F4YU37 F4YU41 F4YZT7 F6KRS6 F6KRU3 F8R147 F8R164 F8R166 F8R185 G0LXY9 G0WVB8 G0WVB9 G0X8R9 G0ZDT3 G0ZDU1 G0ZDU4 G1ENG0 G1EPI8 G3D6J0 H6A2E1 I1W1M6 I6NWI4 I7DB68 L7PEX1 L7YDJ5 M1FUS0 Q000J7 Q7YNW9 Q95IF2 Q9MY59 Q9MY96 Q9UIM8 R4I3H0 R4I4E4 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000498484.1 | HLA-B-004 | 1008 | 224aa | ENSP00000435083.1 | Nonsense mediated decay | A8KNJ4 C7E565 C8CAY1 C9WCW5 C9WEP5 D1G104 D2DL02 D3JTA5 D3U4A4 D3XDF2 D5FHX4 D5FHY3 D5FHZ4 D5FZL0 D5FZL7 D7NPN8 D7R0T8 D9U3H2 E0X600 E0YTL0 E2D5R1 E2GJJ4 E2GJJ5 E2GJK4 E2GJL7 E2GJM1 E3SG96 E3SGA2 E7BYA8 E7EDN6 E9LY43 E9LY52 E9LY54 E9LY55 E9LY57 F2VNK6 F2VNM2 F2X5W7 F4YU37 F4YU41 F4YZT7 F6KRS6 F6KRU3 F8R147 F8R164 F8R166 F8R185 G0LXY9 G0WVB8 G0WVB9 G0X8R9 G0ZDT3 G0ZDU1 G0ZDU4 G1ENG0 G1EPI8 G3D6J0 H6A2E1 I1W1M6 I6NWI4 I7DB68 L7PEX1 L7YDJ5 M1FUS0 Q000J7 Q58P05 Q5QR70 Q5QR71 Q5QR74 Q5QR78 Q66WL2 Q7YNW9 Q8HWR2 Q8HWR3 Q8HWR4 Q8HWR8 Q95IF2 Q9BD04 Q9GIL2 Q9GIZ8 Q9MY59 Q9MY96 Q9UIM8 R4I3H0 R4I4E4 | - | - | |
| ENST00000463832.1 | HLA-B-002 | 1085 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000463600.1 | HLA-B-007 | 917 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000491669.1 | HLA-B-008 | 753 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000475902.1 | HLA-B-005 | 588 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - |
