Description
major histocompatibility complex, class I, B [Source:HGNC Symbol;Acc:4932]
Gene Synonyms
AS, HLA-B59, HLA-DNA, HLA-DRB1, HLAB, MICA, SPDA1
Location
Chromosome HSCHR6_MHC_MANN: 31,364,707-31,368,080 reverse strand.
GRCh37:GL000253.1
View this gene on the primary assembly.
About this gene
This gene has 8 transcripts (splice variants), 1 gene allele and is associated with 2 phenotypes.
Transcripts
| Transcript ID | Name | bp | Protein | Translation ID | Biotype | CCDS | UniProt Match | RefSeq | Flags |
|---|---|---|---|---|---|---|---|---|---|
| ENST00000435618.2 | HLA-B-001 | 1605 | 362aa | ENSP00000405178.2 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | A3F719 A8KNJ4 C5IZS2 C5J017 C6KEB2 C6L831 C7FDR8 C9WCV5 D5FHV3 D5FWD3 D5FZL8 D7NNU9 F4NBX5 F4NBX6 F6KRS4 F8R1A4 G0ZDT6 G1EMM4 G1EPK8 G1EPV2 G9IIV0 I2G867 I3QHS2 I3UI73 I3VZ16 I3VZ18 I6R707 K7P517 N1NUU1 O19669 P03989 P10319 P18465 P30461 P30485 P30487 Q29843 Q29923 Q2L6G2 Q58P05 Q5QR31 Q5QR33 Q5QR34 Q5QR45 Q5QR70 Q5QR71 Q5QR74 Q5QR78 Q66WL2 Q6H8L7 Q6V4Z6 Q710M7 Q710M8 Q7YNW9 Q861E5 Q8HWR2 Q8HWR3 Q8HWR4 Q8HWR8 Q95HA7 Q9BD04 Q9GIL2 Q9GIZ8 Q9MY59 Q9UIM8 R4I4C0 R4I4C2 | - | A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, | |
| ENST00000436729.1 | HLA-B-006 | 1154 | 241aa | ENSP00000403471.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | Q29843 Q5QR31 Q5QR33 Q5QR34 Q5QR45 Q710M7 Q710M8 Q861E5 Q95HA7 | - | 5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete, | |
| ENST00000430299.1 | HLA-B-003 | 820 | 246aa | ENSP00000416672.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | C5IZS2 C5J017 C7FDR8 C9WCV5 D5FHV3 D5FWD3 D5FZL8 D7NNU9 F6KRS4 F8R1A4 G0ZDT6 G1EMM4 G1EPK8 G1EPV2 I3QHS2 I3UI73 I3VZ16 I3VZ18 I6R707 K7P517 O19669 Q6H8L7 Q6V4Z6 Q7YNW9 Q9MY59 Q9UIM8 R4I4C0 R4I4C2 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000481283.1 | HLA-B-004 | 1008 | 224aa | ENSP00000435817.1 | Nonsense mediated decay | A8KNJ4 C5IZS2 C5J017 C7FDR8 C9WCV5 D5FHV3 D5FWD3 D5FZL8 D7NNU9 F6KRS4 F8R1A4 G0ZDT6 G1EMM4 G1EPK8 G1EPV2 I3QHS2 I3UI73 I3VZ16 I3VZ18 I6R707 K7P517 O19669 Q58P05 Q5QR70 Q5QR71 Q5QR74 Q5QR78 Q66WL2 Q6H8L7 Q6V4Z6 Q7YNW9 Q8HWR2 Q8HWR3 Q8HWR4 Q8HWR8 Q9BD04 Q9GIL2 Q9GIZ8 Q9MY59 Q9UIM8 R4I4C0 R4I4C2 | - | - | |
| ENST00000489762.1 | HLA-B-002 | 1085 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000488367.1 | HLA-B-007 | 917 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000492573.1 | HLA-B-008 | 753 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000465455.1 | HLA-B-005 | 588 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - |
