Description
major histocompatibility complex, class I, B [Source:HGNC Symbol;Acc:4932]
Gene Synonyms
AS, HLA-B59, HLA-DNA, HLA-DRB1, HLAB, MICA, SPDA1
Location
Chromosome HSCHR6_MHC_COX: 31,312,134-31,315,506 reverse strand.
GRCh37:GL000251.1
View this gene on the primary assembly.
About this gene
This gene has 8 transcripts (splice variants), 1 gene allele and is associated with 2 phenotypes.
Transcripts
| Transcript ID | Name | bp | Protein | Translation ID | Biotype | CCDS | UniProt Match | RefSeq | Flags |
|---|---|---|---|---|---|---|---|---|---|
| ENST00000425848.2 | HLA-B-001 | 1605 | 362aa | ENSP00000400842.2 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | A2VBY1 A7WPJ0 B5B8Y7 B9VPM1 B9VWB1 C7C5G6 C7FDR9 C9E1F9 C9E1H5 C9E858 D2DKL7 D2DKP0 D2DKQ5 D2DKR8 D2DKS1 D2DKS3 D2DL39 D3U3S1 D3U3S2 D3U3S9 D4HP77 D4HP87 D4HPB1 D4HPK2 D4HPK9 D5FHY6 D5FZK2 D6CIN1 D7NNV2 D7NPQ0 D7NQX1 D7R0U5 E0X9I7 E1U682 E2DH86 E3Q1J1 E3SWH3 E7BYA0 E9LY24 F4YU54 F8RHF4 F8RHH0 G1ENH6 G1EPQ5 G3D6J9 G3D6K1 G9HW80 G9I2K5 I1W1M8 I3VZ14 I3VZ27 I4EC43 I7JHQ8 K0A005 K7P5K3 K9LD82 M1FUS4 M9P8Q9 M9PA20 O19564 O19568 O19691 P30460 P30462 P30475 P30479 Q155X3 Q29843 Q29923 Q2YHP4 Q4VYS9 Q5F311 Q5QR31 Q5QR33 Q5QR34 Q5QR36 Q5QR46 Q5QR47 Q5QR48 Q5QR57 Q5QR58 Q5QR59 Q5QR60 Q5QR62 Q5QR69 Q5QR73 Q5QR76 Q5QR83 Q5QR84 Q5QR85 Q5QR86 Q5QR87 Q5QR88 Q5SS57 Q6IUU8 Q6ZXT6 Q709M5 Q70HJ6 Q710M7 Q710M8 Q7YNX2 Q7YP17 Q861B6 Q861D4 Q861D6 Q861E5 Q8HWM2 Q8HWQ3 Q95365 Q9UE90 Q9UE96 R4ZGR5 | - | A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, | |
| ENST00000416726.1 | HLA-B-006 | 1154 | 241aa | ENSP00000392099.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | B9VWB1 Q29843 Q5F311 Q5QR31 Q5QR33 Q5QR34 Q5QR36 Q5QR46 Q5QR47 Q5QR48 Q5QR57 Q5QR58 Q5QR59 Q5QR60 Q6ZXT6 Q709M5 Q70HJ6 Q710M7 Q710M8 Q7YNX2 Q7YP17 Q861D4 Q861D6 Q861E5 Q8HWQ3 | - | 5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete, | |
| ENST00000445222.1 | HLA-B-003 | 863 | 246aa | ENSP00000399675.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | A2VBY1 B5B8Y7 B9VPM1 C7C5G6 C7FDR9 C9E1F9 C9E1H5 C9E858 D2DKL7 D2DKP0 D2DKQ5 D2DKR8 D2DKS1 D2DKS3 D2DL39 D3U3S1 D3U3S2 D3U3S9 D4HP77 D4HP87 D4HPB1 D4HPK2 D4HPK9 D5FHY6 D5FZK2 D7NNV2 D7NPQ0 D7NQX1 D7R0U5 E0X9I7 E1U682 E2DH86 E3SWH3 E7BYA0 E9LY24 F4YU54 F8RHF4 F8RHH0 G1ENH6 G1EPQ5 G3D6J9 G3D6K1 G9HW80 G9I2K5 I1W1M8 I3VZ14 I3VZ27 K0A005 K7P5K3 K9LD82 M1FUS4 M9P8Q9 M9PA20 O19564 O19568 Q155X3 Q2YHP4 Q4VYS9 Q8HWM2 Q9UE90 Q9UE96 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000461583.1 | HLA-B-004 | 1008 | 224aa | ENSP00000436637.1 | Nonsense mediated decay | A2VBY1 B5B8Y7 B9VPM1 C7C5G6 C7FDR9 C9E1F9 C9E1H5 C9E858 D2DKL7 D2DKP0 D2DKQ5 D2DKR8 D2DKS1 D2DKS3 D2DL39 D3U3S1 D3U3S2 D3U3S9 D4HP77 D4HP87 D4HPB1 D4HPK2 D4HPK9 D5FHY6 D5FZK2 D7NNV2 D7NPQ0 D7NQX1 D7R0U5 E0X9I7 E1U682 E2DH86 E3SWH3 E7BYA0 E9LY24 F4YU54 F8RHF4 F8RHH0 G1ENH6 G1EPQ5 G3D6J9 G3D6K1 G9HW80 G9I2K5 I1W1M8 I3VZ14 I3VZ27 K0A005 K7P5K3 K9LD82 M1FUS4 M9P8Q9 M9PA20 O19564 O19568 Q155X3 Q2YHP4 Q4VYS9 Q5QR62 Q5QR69 Q5QR73 Q5QR76 Q5QR83 Q5QR84 Q5QR85 Q5QR86 Q5QR87 Q5QR88 Q8HWM2 Q9UE90 Q9UE96 | - | - | |
| ENST00000470915.1 | HLA-B-002 | 1088 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000473379.1 | HLA-B-007 | 917 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000472294.1 | HLA-B-008 | 753 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000490676.1 | HLA-B-005 | 586 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - |
