Description
major histocompatibility complex, class I, B [Source:HGNC Symbol;Acc:4932]
Gene Synonyms
AS, HLA-B59, HLA-DNA, HLA-DRB1, HLAB, MICA, SPDA1
Location
Chromosome HSCHR6_MHC_QBL: 31,311,768-31,315,097 reverse strand.
GRCh37:GL000255.1
View this gene on the primary assembly.
About this gene
This gene has 8 transcripts (splice variants), 1 gene allele and is associated with 2 phenotypes.
Transcripts
| Transcript ID | Name | bp | Protein | Translation ID | Biotype | CCDS | UniProt Match | RefSeq | Flags |
|---|---|---|---|---|---|---|---|---|---|
| ENST00000359635.5 | HLA-B-001 | 1561 | 362aa | ENSP00000352656.5 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | B9VWB1 C7FDS0 C9WD04 D1G0T5 D3U467 D3XDG1 D5FWB7 D5FZK3 E9LY27 E9LY28 E9LY47 F2X5V1 F4YU34 F4YZU8 F4YZV1 F8R161 F8R8J1 F8T957 G0ZDT8 G1EMN0 G1EPK5 G1EPQ9 G9HW40 H9BQ98 I6M554 I6MHH7 I6MHI1 I6MHI4 I6NN10 I6NS75 I6NXF7 I6QQT3 I7APH9 K4JES8 K7P5G2 K9L8C4 L0BVL7 L7PG40 M1F364 M1FUU1 M9WLY3 O78177 P18463 P18464 P30466 P30491 P30492 P30493 P30495 P30498 P30685 Q04826 Q08GD2 Q09JY6 Q29718 Q29843 Q29940 Q30210 Q4ZHW0 Q58P05 Q5F311 Q5QR28 Q5QR32 Q5QR35 Q5QR37 Q5QR39 Q5QR40 Q5QR41 Q5QR44 Q5QR47 Q5QR52 Q5QR53 Q5QR54 Q5QR55 Q5QR56 Q5QR70 Q5QR71 Q5QR74 Q5QR78 Q66WL2 Q6ZXT6 Q709M5 Q70HJ6 Q70HJ8 Q7YNX2 Q7YP17 Q861D4 Q861D6 Q861D8 Q861D9 Q861E0 Q861E1 Q861E2 Q861E3 Q861E4 Q8HWQ3 Q8HWR2 Q8HWR3 Q8HWR4 Q8HWR8 Q8HWS8 Q8MGY8 Q8MHM9 Q8WLT1 Q9GIL8 Q9GIZ8 S6AU73 | - | A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, | |
| ENST00000418147.1 | HLA-B-006 | 1154 | 241aa | ENSP00000411954.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | B9VWB1 Q29843 Q5F311 Q5QR28 Q5QR32 Q5QR35 Q5QR37 Q5QR39 Q5QR40 Q5QR41 Q5QR44 Q5QR47 Q5QR52 Q5QR53 Q5QR54 Q5QR55 Q5QR56 Q6ZXT6 Q709M5 Q70HJ6 Q7YNX2 Q7YP17 Q861D4 Q861D6 Q861D8 Q861D9 Q861E0 Q861E1 Q861E2 Q861E3 Q861E4 Q8HWQ3 Q8MGY8 | - | 5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete, | |
| ENST00000479203.1 | HLA-B-004 | 1005 | 224aa | ENSP00000433363.1 | Nonsense mediated decay | C7FDS0 C9WD04 D1G0T5 D3U467 D3XDG1 D5FWB7 D5FZK3 E9LY27 E9LY28 E9LY47 F2X5V1 F4YU34 F4YZU8 F4YZV1 F8R161 F8R8J1 F8T957 G0ZDT8 G1EMN0 G1EPK5 G1EPQ9 G9HW40 H9BQ98 I6M554 I6MHH7 I6MHI1 I6MHI4 I6NN10 I6NS75 I6NXF7 I6QQT3 I7APH9 K4JES8 K7P5G2 K9L8C4 L0BVL7 L7PG40 M1F364 M1FUU1 M9WLY3 O78177 Q08GD2 Q4ZHW0 Q58P05 Q5QR70 Q5QR71 Q5QR74 Q5QR78 Q66WL2 Q70HJ8 Q8HWR2 Q8HWR3 Q8HWR4 Q8HWR8 Q8HWS8 Q8MHM9 Q8WLT1 Q9GIL8 Q9GIZ8 | - | - | |
| ENST00000493512.1 | HLA-B-002 | 1088 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000479990.1 | HLA-B-007 | 917 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000466304.1 | HLA-B-003 | 863 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000490054.1 | HLA-B-008 | 753 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000475493.1 | HLA-B-005 | 585 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - |
