Gene: STAT3 ENSG00000168610

Description

signal transducer and activator of transcription 3 (acute-phase response factor) [Source:HGNC Symbol;Acc:11364]

Gene Synonyms

APRF, HIES

Location

Chromosome 17: 40,465,342-40,540,586 reverse strand.

GRCh37:CM000679.1

About this gene

This gene has 14 transcripts (splice variants), 6 paralogues and is associated with 73 phenotypes.

Transcripts

Show transcript tableHide transcript table

Transcript ID	Name	bp	Protein	Translation ID	Biotype	UniProt Match	Flags
ENST00000264657.5	STAT3-001	5047	770aa	ENSP00000264657.4	Gene/transcipt that contains an open reading frame (ORF).Protein coding	G8JLH9 P40763	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000389272.3	STAT3-013	2615	672aa	ENSP00000373923.3	Gene/transcipt that contains an open reading frame (ORF).Protein coding	G8JLH9	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000404395.3	STAT3-002	2633	769aa	ENSP00000384943.3	Gene/transcipt that contains an open reading frame (ORF).Protein coding	P40763	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000462269.1	STAT3-006	698	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron	-	-
ENST00000462286.2	STAT3-014	1982	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron	-	-
ENST00000471989.1	STAT3-005	826	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron	-	-
ENST00000478276.1	STAT3-003	186	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron	-	-
ENST00000491272.1	STAT3-007	725	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron	-	-
ENST00000498330.1	STAT3-004	559	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron	-	-
ENST00000585360.1	STAT3-017	517	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron	-	-
ENST00000585517.1	STAT3-012	3319	722aa	ENSP00000467000.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding	K7ENL3	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000588065.1	STAT3-016	571	84aa	ENSP00000467173.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding	K7EP08	3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENST00000588969.1	STAT3-011	2772	770aa	ENSP00000467985.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding	G8JLH9 P40763	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000590776.1	STAT3-015	1483	No protein	-	Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript	-	-

Summary

Name

STAT3 (HGNC Symbol)

UniProtKB

This gene has proteins that correspond to the following UniProtKB identifiers: P40763

CCDS

This gene is a member of the Human CCDS set: CCDS32656.1, CCDS32657.1, CCDS59288.1

LRG

LRG_112 provides a stable genomic reference framework for describing sequence variants for this gene

Ensembl version

ENSG00000168610.10

Other assemblies

This gene maps to 42,313,324-42,388,568 in GRCh38 coordinates.

Gene type

Protein coding

Annotation method

Annotation for this gene includes both automatic annotation from Ensembl and Havana manual curation, see article.

Alternative genes

This gene corresponds to the following database identifiers:

Havana gene:	OTTHUMG00000150645 (version 3)

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Gene: STAT3 ENSG00000168610

Summary